製品: UBXD5 Mouse Monoclonal Antibody
カタログ: BF8989
タンパク質の説明: Mouse monoclonal antibody to UBXD5
アプリケーション: WB
反応性: Human
予測: Mouse, Rat, Pig, Bovine, Sheep, Rabbit
分子量: 57kDa; 57kD(Calculated).
ユニプロット: Q5T124

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8989]
特異性:
UBXD5 Mouse Monoclonal Antibody detects endogenous levels of total UBXD5.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

COA 1; colorectal tumor associated antigen 1; Colorectal tumor associated antigen COA 1; PP2243; SOC; SOCI; Socius; UBX domain containing 5; UBX domain containing protein 11; UBX domain containing protein 5; UBXD 5; UBXN11;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質の説明:
UBXN11 May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13. Interacts with GNA12, GNA13, RND1, RND2 AND RND3. 8 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
タンパク質配列:
MSSPLASLSKTRKVPLPSEPMNPGRRGIRIYGDEDEVDMLSDGCGSEEKISVPSCYGGIGAPVSRQVPASHDSELMAFMTRKLWDLEQQVKAQTDEILSKDQKIAALEDLVQTLRPHPAEATLQRQEELETMCVQLQRQVREMERFLSDYGLQWVGEPMDQEDSESKTVSEHGERDWMTAKKFWKPGDSLAPPEVDFDRLLASLQDLSELVVEGDTQVTPVPGGARLRTLEPIPLKLYRNGIMMFDGPFQPFYDPSTQRCLRDILDGFFPSELQRLYPNGVPFKVSDLRNQVYLEDGLDPFPGEGRVVGRQLMHKALDRVEEHPGSRMTAEKFLNRLPKFVIRQGEVIDIRGPIRDTLQNCCPLPARIQEIVVETPTLAAERERSQESPNTPAPPLSMLRIKSENGEQAFLLMMQPDNTIGDVRALLAQARVMDASAFEIFSTFPPTLYQDDTLTLQAAGLVPKAALLLRARRAPKSSLKFSPGPCPGPGPGPSPGPGPGPSPGPGPGPSPCPGPSPSPQ

PTMs - Q5T124 基板として

Site PTM Type Enzyme
S3 Phosphorylation
S9 Phosphorylation
K13 Ubiquitination
S70 Phosphorylation
S73 Phosphorylation
T80 Phosphorylation
K100 Ubiquitination
S208 Phosphorylation
K236 Ubiquitination
K284 Ubiquitination
K402 Ubiquitination

研究背景

機能:

May be involved in the reorganization of actin cytoskeleton mediated by RND1, RND2 AND RND3. Promotes RHOA activation mediated by GNA12 and GNA13 (By similarity).

細胞の位置付け:

Cytoplasm>Cytoskeleton.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with GNA12, GNA13, RND1, RND2 AND RND3.

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