製品: VWA5A Mouse Monoclonal Antibody
カタログ: BF9351
タンパク質の説明: Mouse monoclonal antibody to VWA5A
アプリケーション: WB
反応性: Human
予測: Human, Horse, Dog
分子量: 86 KD; 86kD(Calculated).
ユニプロット: O00534

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm9351]
特異性:
VWA5A Mouse Monoclonal Antibody detects endogenous levels of total VWA5A.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

BCSC 1;BCSC-1;BCSC1;Breast cancer suppressor candidate 1;LHR2A;LOH11CR2A;Loss of heterozygosity 11 chromosomal region 2 gene A;Loss of heterozygosity 11 chromosomal region 2 gene A protein;Ortholog of mouse AW551984;VMA5A_HUMAN;von Willebrand factor A domain containing 5A;von Willebrand factor A domain-containing protein 5A;Vwa5a;

免疫原

免疫原:

A synthesized peptide derived from human VWA5A, corresponding to a region within the internal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
O00534 VMA5A_HUMAN:

Expressed at low level in many tissues. Not expressed in 80% of tumor cell lines tested.

タンパク質配列:
MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLSAKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPDVNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQGPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSASQPRGELMCYKAKTFQMDDYSLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELVDSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAGSTMPSVVKAAITFLKSSVDPAIFAF

研究背景

機能:

May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.

組織特異性:

Expressed at low level in many tissues. Not expressed in 80% of tumor cell lines tested.

Restrictive clause

 

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