製品: MRPL39 Mouse Monoclonal Antibody
カタログ: BF9359
タンパク質の説明: Mouse monoclonal antibody to MRPL39
アプリケーション: WB
反応性: Human
予測: Mouse, Rat, Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 39 KD; 39kD(Calculated).
ユニプロット: Q9NYK5

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm9359]
特異性:
MRPL39 Mouse Monoclonal Antibody detects endogenous levels of total MRPL39.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

39S ribosomal protein L39, mitochondrial; 39S ribosomal protein L5, mitochondrial; C21orf92; FLJ20451; L39mt; L5mt; MGC104174; MGC3400; Mitochondrial ribosomal protein L39; MRP L39; MRP L5; MRP-L39; MRP-L5; MRPL5; MSTP003; OTTHUMP00000095992; PRED22; PRED66; RPML5;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9NYK5 RM39_HUMAN:

Isoform 1 is ubiquitously expressed. Isoform 2 is heart-specific.

タンパク質配列:
MEALAMGSRALRLWLVAPGGGIKWRFIATSSASQLSPTELTEMRNDLFNKEKARQLSLTPRTEKIEVKHVGKTDPGTVFVMNKNISTPYSCAMHLSEWYCRKSILALVDGQPWDMYKPLTKSCEIKFLTFKDCDPGEVNKAYWRSCAMMMGCVIERAFKDEYMVNLVRAPEVPVISGAFCYDVVLDSKLDEWMPTKENLRSFTKDAHALIYKDLPFETLEVEAKVALEIFQHSKYKVDFIEEKASQNPERIVKLHRIGDFIDVSEGPLIPRTSICFQYEVSAVHNLQPTQPSLIRRFQGVSLPVHLRAHFTIWDKLLERSRKMVTEDQSKATEECTST

PTMs - Q9NYK5 基板として

Site PTM Type Enzyme
K50 Ubiquitination
T59 Phosphorylation
K72 Acetylation
K72 Ubiquitination
S96 Phosphorylation
Y99 Phosphorylation
K126 Acetylation
K131 Ubiquitination
K196 Ubiquitination
R200 Methylation
K204 Acetylation
K204 Ubiquitination
K236 Ubiquitination
K243 Ubiquitination
K253 Methylation
K315 Ubiquitination
T325 Phosphorylation
S329 Phosphorylation
T332 Phosphorylation
C335 S-Nitrosylation

研究背景

細胞の位置付け:

Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Isoform 1 is ubiquitously expressed. Isoform 2 is heart-specific.

サブユニット構造:

Component of the mitochondrial large ribosomal subunit (mt-LSU). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins.

タンパク質ファミリー:

Belongs to the mitochondrion-specific ribosomal protein mL39 family.

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