製品: AE2 Mouse Monoclonal Antibody
カタログ: BF9418
タンパク質の説明: Mouse monoclonal antibody to AE2
アプリケーション: WB
反応性: Human
予測: Mouse, Rat, Pig, Bovine, Sheep, Dog
分子量: 137 kDa; 137kD(Calculated).
ユニプロット: P04920

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm9418]
特異性:
AE2 Mouse Monoclonal Antibody detects endogenous levels of total AE2.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

AE 2; AE2 anion exchanger; Anion exchange protein 2; Anion exchanger 2; B3A2_HUMAN; BAND 3-LIKE PROTEIN; BND3L; EPB3L1; erythrocyte band 3; Erythrocyte membrane protein band 3 like 1; HKB3; MPB3L; NBND3; Non-erythroid band 3-like protein; Slc4a2; Solute carrier family 4 member 2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MSSAPRRPAKGADSFCTPEPESLGPGTPGFPEQEEDELHRTLGVERFEEILQEAGSRGGEEPGRSYGEEDFEYHRQSSHHIHHPLSTHLPPDARRRKTPQGPGRKPRRRPGASPTGETPTIEEGEEDEDEASEAEGARALTQPSPVSTPSSVQFFLQEDDSADRKAERTSPSSPAPLPHQEATPRASKGAQAGTQVEEAEAEAVAVASGTAGGDDGGASGRPLPKAQPGHRSYNLQERRRIGSMTGAEQALLPRVPTDEIEAQTLATADLDLMKSHRFEDVPGVRRHLVRKNAKGSTQSGREGREPGPTPRARPRAPHKPHEVFVELNELLLDKNQEPQWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRTLAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLLKHSHPSDEKDFSFPRNISAGSLGSLLGHHHGQGAESDPHVTEPLMGGVPETRLEVERERELPPPAPPAGITRSKSKHELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLLLGPSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQGEELLRSVAHFQRQMLKKREEQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAEDDPLRRTGRPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIGVSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWIGFWLVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHGCSASNSSEVDGGENMTWAGARPTLGPGNRSLAGQSGQGKPRGQPNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMVLVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAILVFILIFMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANALTVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFLYMGVTSLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMSTAASLAFPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDEYNEMPMPV

PTMs - P04920 基板として

Site PTM Type Enzyme
T27 Phosphorylation
S56 Phosphorylation
R57 Methylation
S65 Phosphorylation
Y66 Phosphorylation
Y73 Phosphorylation
S113 Phosphorylation
T115 Phosphorylation
T118 Phosphorylation
S132 Phosphorylation
S144 Phosphorylation
T148 Phosphorylation
S150 Phosphorylation
S151 Phosphorylation
T169 Phosphorylation
S170 Phosphorylation
S172 Phosphorylation
S173 Phosphorylation
T183 Phosphorylation
S232 Phosphorylation
Y233 Phosphorylation
S243 Phosphorylation
T245 Phosphorylation
T257 Phosphorylation
T264 Phosphorylation
K274 Methylation
T309 Phosphorylation
K319 Ubiquitination
K334 Ubiquitination
K362 Ubiquitination
K426 Ubiquitination
K434 Ubiquitination
S443 Phosphorylation
S446 Phosphorylation
S449 Phosphorylation
S461 Phosphorylation
S500 Phosphorylation
K505 Ubiquitination
K636 Ubiquitination
K653 Ubiquitination
K658 Ubiquitination
K893 Ubiquitination
K975 Ubiquitination
K1073 Ubiquitination
K1080 Ubiquitination
K1087 Ubiquitination
Y1154 Phosphorylation
K1156 Ubiquitination
Y1234 Phosphorylation

研究背景

機能:

Plasma membrane anion exchange protein of wide distribution.

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the anion exchanger (TC 2.A.31) family.

研究領域

· Organismal Systems > Digestive system > Salivary secretion.

· Organismal Systems > Digestive system > Gastric acid secretion.

· Organismal Systems > Digestive system > Pancreatic secretion.

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