AFfirm™ FAKD5 Mouse Monoclonal Antibody - #BF9423
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
dJ1187M17.5; FAKD5_HUMAN; FAST kinase domain-containing protein 5; FAST kinase domains 5; FASTKD5; FLJ13149; FLJ58294;
免疫原
Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle, liver and thyroid.
- Q7L8L6 FAKD5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAATLKSLKLVRYRAFCSPSAFGAVRSVSYWNVSSTQHGGQDPPEHISLCHSAKKVKNICSTFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQLRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPVLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKPLPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENKAAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL
PTMs - Q7L8L6 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S7 | Phosphorylation | Uniprot | |
| S73 | Phosphorylation | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| K82 | Ubiquitination | Uniprot | |
| T83 | Phosphorylation | Uniprot | |
| K87 | Ubiquitination | Uniprot | |
| S95 | Phosphorylation | Uniprot | |
| T99 | Phosphorylation | Uniprot | |
| Y166 | Phosphorylation | Uniprot | |
| S171 | Phosphorylation | Uniprot | |
| K361 | Ubiquitination | Uniprot | |
| Y451 | Phosphorylation | Uniprot | |
| K507 | Acetylation | Uniprot | |
| T608 | Phosphorylation | Uniprot | |
| K615 | Ubiquitination | Uniprot | |
| C670 | S-Nitrosylation | Uniprot | |
| S676 | Phosphorylation | Uniprot | |
| T692 | Phosphorylation | Uniprot | |
| R704 | Methylation | Uniprot | |
| Y730 | Phosphorylation | Uniprot | |
| T761 | Phosphorylation | Uniprot | |
| S762 | Phosphorylation | Uniprot |
研究背景
Plays an important role in the processing of non-canonical mitochondrial mRNA precursors.
Mitochondrion matrix>Mitochondrion nucleoid.
Note: Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids.
Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart, smooth muscle, liver and thyroid.
Found in a complex with GRSF1, DDX28, DHX30 and FASTKD2. Associates with the 12S mitochondrial rRNA (12S mt-rRNA).
Belongs to the FAST kinase family.
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For Research Use Only.
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