AFfirm™ POLG1 Mouse Monoclonal Antibody - #BF9444
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
DNA directed DNA polymerase gamma; DNA polymerase subunit gamma 1; DNA polymerase subunit gamma-1; DPOG1_HUMAN; MDP 1; MDP1; Mitochondrial DNA polymerase catalytic subunit; Mitochondrial DNA polymerase gamma; PEO; POLG 1; POLG A; PolG alpha; POLG; PolG-alpha; POLG1; POLGA; Polymerase (DNA directed) gamma; SANDO; SCAE;
免疫原
- P54098 DPOG1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSRLLWRKVAGATVGPGPVPAPGRWVSSSVPASDPSDGQRRRQQQQQQQQQQQQQPQQPQVLSSEGGQLRHNPLDIQMLSRGLHEQIFGQGGEMPGEAAVRRSVEHLQKHGLWGQPAVPLPDVELRLPPLYGDNLDQHFRLLAQKQSLPYLEAANLLLQAQLPPKPPAWAWAEGWTRYGPEGEAVPVAIPEERALVFDVEVCLAEGTCPTLAVAISPSAWYSWCSQRLVEERYSWTSQLSPADLIPLEVPTGASSPTQRDWQEQLVVGHNVSFDRAHIREQYLIQGSRMRFLDTMSMHMAISGLSSFQRSLWIAAKQGKHKVQPPTKQGQKSQRKARRGPAISSWDWLDISSVNSLAEVHRLYVGGPPLEKEPRELFVKGTMKDIRENFQDLMQYCAQDVWATHEVFQQQLPLFLERCPHPVTLAGMLEMGVSYLPVNQNWERYLAEAQGTYEELQREMKKSLMDLANDACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKEPATASKLPIEGAGAPGDPMDQEDLGPCSEEEEFQQDVMARACLQKLKGTTELLPKRPQHLPGHPGWYRKLCPRLDDPAWTPGPSLLSLQMRVTPKLMALTWDGFPLHYSERHGWGYLVPGRRDNLAKLPTGTTLESAGVVCPYRAIESLYRKHCLEQGKQQLMPQEAGLAEEFLLTDNSAIWQTVEELDYLEVEAEAKMENLRAAVPGQPLALTARGGPKDTQPSYHHGNGPYNDVDIPGCWFFKLPHKDGNSCNVGSPFAKDFLPKMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALPRAVIRHPDYDEEGLYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGSELKAMVQAPPGYTLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQGRKSRGTDLHSKTATTVGISREHAKIFNYGRIYGAGQPFAERLLMQFNHRLTQQEAAEKAQQMYAATKGLRWYRLSDEGEWLVRELNLPVDRTEGGWISLQDLRKVQRETARKSQWKKWEVVAERAWKGGTESEMFNKLESIATSDIPRTPVLGCCISRALEPSAVQEEFMTSRVNWVVQSSAVDYLHLMLVAMKWLFEEFAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLNDLPQSVAFFSAVDIDRCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQIIELTKGSLEKRSQPGP
PTMs - P54098 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K109 | Ubiquitination | Uniprot | |
| S296 | Phosphorylation | Uniprot | |
| K316 | Ubiquitination | Uniprot | |
| K321 | Ubiquitination | Uniprot | |
| K327 | Ubiquitination | Uniprot | |
| K371 | Ubiquitination | Uniprot | |
| K379 | Ubiquitination | Uniprot | |
| K383 | Ubiquitination | Uniprot | |
| S433 | Phosphorylation | Uniprot | |
| Y479 | Phosphorylation | Uniprot | |
| K551 | Ubiquitination | Uniprot | |
| K553 | Ubiquitination | Uniprot | |
| K561 | Ubiquitination | Uniprot | |
| K633 | Ubiquitination | Uniprot | |
| K658 | Ubiquitination | Uniprot | |
| K726 | Ubiquitination | Uniprot | |
| K755 | Ubiquitination | Uniprot | |
| K768 | Ubiquitination | Uniprot | |
| K773 | Ubiquitination | Uniprot | |
| K796 | Ubiquitination | Uniprot | |
| K934 | Ubiquitination | Uniprot | |
| K947 | Ubiquitination | Uniprot | |
| K981 | Ubiquitination | Uniprot | |
| K990 | Ubiquitination | Uniprot | |
| R1014 | Methylation | Uniprot | |
| K1040 | Ubiquitination | Uniprot | |
| K1050 | Ubiquitination | Uniprot | |
| K1060 | Ubiquitination | Uniprot | |
| K1191 | Ubiquitination | Uniprot | |
| K1198 | Ubiquitination | Uniprot | |
| Y1221 | Phosphorylation | Uniprot |
研究背景
Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
Mitochondrion. Mitochondrion matrix>Mitochondrion nucleoid.
Heterotrimer composed of a catalytic subunit and a homodimer of accessory subunits (By similarity). Interacts with TTC3.
Belongs to the DNA polymerase type-A family.
研究領域
· Metabolism > Global and overview maps > Metabolic pathways.
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