AFfirm™ FKBPL Mouse Monoclonal Antibody - #BF9482
製品説明
ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human
クローナリティ:
Monoclonal [AFfirm9482]
特異性:
FKBPL Mouse Monoclonal Antibody detects endogenous levels of total FKBPL.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
DIR1; FK506 binding protein like; FK506-binding protein-like; Fkbpl; FKBPL_HUMAN; NG7; OTTHUMP00000029170; WAF 1/CIP1 stabilizing protein 39; WAF-1/CIP1 stabilizing protein 39; WISP39;
免疫原
免疫原:
A synthesized peptide derived from human FKBPL, corresponding to a region within the internal amino acids.
Uniprot:
遺伝子(ID):
発現特異性:
タンパク質の説明:
FKBPL May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21. Forms a ternary complex with CDKN1A/p21 and HSP90AB1/Hsp90.
タンパク質配列:
- Q9UIM3 FKBPL_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
METPPVNTIGEKDTSQPQQEWEKNLRENLDSVIQIRQQPRDPPTETLELEVSPDPASQILEHTQGAEKLVAELEGDSHKSHGSTSQMPEALQASDLWYCPDGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPWREETWGELIEKCLESMCQGEEAELQLPGHSGPPVRLTLASFTQGRDSWELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPERTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATADLKKVLAIDPKNRAAQEELGKVVIQGKNQDAGLAQGLRKMFG
研究背景
機能:
May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.
組織特異性:
Ubiquitously expressed with higher levels in testis.
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