AFfirm™ VPS37A Mouse Monoclonal Antibody - #BF9509

製品: VPS37A Mouse Monoclonal Antibody
カタログ: BF9509
タンパク質の説明: Mouse monoclonal antibody to VPS37A
アプリケーション: WB
反応性: Human
予測: Mouse, Rat, Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 45 kDa; 44kD(Calculated).
ユニプロット: Q8NEZ2

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm9509]
特異性:
VPS37A Mouse Monoclonal Antibody detects endogenous levels of total VPS37A.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

2210018P21Rik; 4930592A21Rik; AW261445; D8Ertd531e; ESCRT I complex subunit VPS37A; FLJ32642; FLJ42616; HCRP1; hepatocellular carcinoma related protein 1; hVps37A; MGC116266; polyglutamine binding protein 2; PQBP2; vacuolar protein sorting 37A; Vacuolar protein sorting associated protein 37A;

免疫原

免疫原:

A synthesized peptide derived from human VPS37A, corresponding to a region within N-terminal amino acids.

Uniprot:

Q8NEZ2(VP37A_HUMAN) >>Visit HPA database.

遺伝子(ID):
VPS37A(137492)
発現特異性:
Q8NEZ2 VP37A_HUMAN:

Widely expressed. Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. More abundant in liver. Strongly decreased or undetected in hepatomas.

タンパク質配列:
MSWLFPLTKSASSSAAGSPGGLTSLQQQKQRLIESLRNSHSSIAEIQKDVEYRLPFTINNLTININILLPPQFPQEKPVISVYPPIRHHLMDKQGVYVTSPLVNNFTMHSDLGKIIQSLLDEFWKNPPVLAPTSTAFPYLYSNPSGMSPYASQGFPFLPPYPPQEANRSITSLSVADTVSSSTTSHTTAKPAAPSFGVLSNLPLPIPTVDASIPTSQNGFGYKMPDVPDAFPELSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQTVLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKMEIDDFLSSFMEKRTICHCRRAKEEKLQQAIAMHSQFHAPL

研究背景

機能:

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.

細胞の位置付け:

Late endosome membrane>Peripheral membrane protein. Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Widely expressed. Examined tissues include heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. More abundant in liver. Strongly decreased or undetected in hepatomas.

タンパク質ファミリー:

Belongs to the VPS37 family.

研究領域

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

Restrictive clause

 

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