ER81 Antibody - #DF3193
| 製品: | ER81 Antibody |
| カタログ: | DF3193 |
| タンパク質の説明: | Rabbit polyclonal antibody to ER81 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 60 KD; 55kD(Calculated). |
| ユニプロット: | P50549 |
| RRID: | AB_2835416 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3193, RRID:AB_2835416.
折りたたみ／展開
DKFZp781L0674; ER81; ER81 protein; ER81, mouse, homolog of; ETS translocation variant 1; ets variant gene 1; Ets-related protein 81; Etsrp81; ETV 1; ETV1; ETV1_HUMAN; MGC104699; MGC120533; MGC120534;
免疫原
Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.
- P50549 ETV1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDGFYDQQVPYMVTNSQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSEISSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSTHTPKPDRAFPAHLPPSQSIPDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGSAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLAHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P50549 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y5 | Phosphorylation | Uniprot | |
| K33 | Acetylation | Uniprot | |
| S94 | Phosphorylation | Uniprot | |
| S97 | Phosphorylation | Uniprot | |
| K116 | Acetylation | Uniprot | |
| T139 | Phosphorylation | Uniprot | |
| T143 | Phosphorylation | Uniprot | |
| S146 | Phosphorylation | Uniprot | |
| S191 | Phosphorylation | O75582 (RPS6KA5) , Q15418 (RPS6KA1) , P17612 (PRKACA) , P49137 (MAPKAPK2) | Uniprot |
| S216 | Phosphorylation | P17612 (PRKACA) , P49137 (MAPKAPK2) , O75582 (RPS6KA5) , Q15418 (RPS6KA1) | Uniprot |
| S334 | Phosphorylation | P17612 (PRKACA) , Q15418 (RPS6KA1) | Uniprot |
| Y410 | Phosphorylation | Uniprot |
研究背景
Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
Sumoylated.
Phosphorylated at Ser-191 and Ser-216 by RPS6KA1 and RPS6KA5; phosphorylation activates transcriptional activity.
Nucleus.
Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.
Belongs to the ETS family.
研究領域
· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.
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