HMG17 Antibody - #DF3070
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3070, RRID:AB_2835453.
折りたたみ／展開
High mobility group (nonhistone chromosomal) protein 17; high mobility group nucleosomal binding domain 2; High mobility group nucleosome-binding domain-containing protein 2; High mobility group protein N2; HMG17; HMGN2; HMGN2_HUMAN; MGC5629; Non histone chromosomal protein HMG 17; Non-histone chromosomal protein HMG-17; Nonhistone chromosomal protein HMG 17; nonhistone chromosomal protein hmg-17;
免疫原
- P05204 HMGN2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKEGNNPAENGDAKTDQAQKAEGAGDAK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P05204 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| K3 | Acetylation | Uniprot | |
| K5 | Acetylation | Uniprot | |
| K11 | Acetylation | Uniprot | |
| K14 | Acetylation | Uniprot | |
| K18 | Sumoylation | Uniprot | |
| S25 | Phosphorylation | Q96GD4 (AURKB) , P17252 (PRKCA) , P17612 (PRKACA) , P51812 (RPS6KA3) | Uniprot |
| S29 | Phosphorylation | P17252 (PRKCA) , Q96GD4 (AURKB) , P51812 (RPS6KA3) , P17612 (PRKACA) | Uniprot |
| K31 | Acetylation | Uniprot | |
| K31 | Ubiquitination | Uniprot | |
| K36 | Acetylation | Uniprot | |
| K36 | Sumoylation | Uniprot | |
| K36 | Ubiquitination | Uniprot | |
| K40 | Acetylation | Uniprot | |
| K40 | Ubiquitination | Uniprot | |
| K47 | Ubiquitination | Uniprot | |
| K48 | Ubiquitination | Uniprot | |
| K51 | Ubiquitination | Uniprot | |
| K54 | Acetylation | Uniprot | |
| K56 | Acetylation | Uniprot | |
| K57 | Acetylation | Uniprot | |
| K59 | Acetylation | Uniprot | |
| K64 | Acetylation | Uniprot | |
| K64 | Ubiquitination | Uniprot | |
| K76 | Acetylation | Uniprot | |
| K76 | Ubiquitination | Uniprot | |
| K82 | Acetylation | Uniprot | |
| K82 | Sumoylation | Uniprot | |
| K82 | Ubiquitination | Uniprot | |
| K90 | Acetylation | Uniprot |
研究背景
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity).
Phosphorylation favors cytoplasmic localization.
Nucleus. Cytoplasm.
Note: Cytoplasmic enrichment upon phosphorylation.
Belongs to the HMGN family.
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