GLU2B Antibody - #DF3092
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3092, RRID:AB_2835475.
折りたたみ／展開
80K-H protein; AGE-binding receptor 2; AGE-R2; G19P1; GLU2B_HUMAN; Glucosidase 2 subunit beta; Glucosidase II beta subunit; Glucosidase II subunit beta; Hepatocystin; PCLD; PKCSH; PLD1; PRKCSH; Protein kinase C substrate 60.1 kDa protein heavy chain; Protein kinase C substrate 80 Kda protein; Protein kinase C substrate 80K-H; Protein kinase C substrate, 80 Kda protein;
免疫原
- P14314 GLU2B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLLPLLLLLPMCWAVEVKRPRGVSLTNHHFYDESKPFTCLDGSATIPFDQVNDDYCDCKDGSDEPGTAACPNGSFHCTNTGYKPLYIPSNRVNDGVCDCCDGTDEYNSGVICENTCKEKGRKERESLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPAPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTTNEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P14314 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S24 | Phosphorylation | Uniprot | |
| K83 | Methylation | Uniprot | |
| K83 | Ubiquitination | Uniprot | |
| S126 | Phosphorylation | Uniprot | |
| T134 | O-Glycosylation | Uniprot | |
| K142 | Ubiquitination | Uniprot | |
| K166 | Ubiquitination | Uniprot | |
| K167 | Ubiquitination | Uniprot | |
| S168 | Phosphorylation | Uniprot | |
| R177 | Methylation | Uniprot | |
| K196 | Ubiquitination | Uniprot | |
| K206 | Ubiquitination | Uniprot | |
| T287 | O-Glycosylation | Uniprot | |
| S293 | O-Glycosylation | Uniprot | |
| S343 | Phosphorylation | Uniprot | |
| S349 | Phosphorylation | Uniprot | |
| K376 | Ubiquitination | Uniprot | |
| K385 | Ubiquitination | Uniprot | |
| Y423 | Phosphorylation | Uniprot | |
| K436 | Ubiquitination | Uniprot | |
| K438 | Ubiquitination | Uniprot | |
| S442 | Phosphorylation | Uniprot | |
| T448 | Phosphorylation | Uniprot | |
| S451 | Phosphorylation | Uniprot | |
| K459 | Acetylation | Uniprot | |
| K459 | Ubiquitination | Uniprot | |
| K464 | Ubiquitination | Uniprot | |
| K487 | Ubiquitination | Uniprot | |
| T494 | Phosphorylation | Uniprot | |
| S498 | Phosphorylation | Uniprot |
研究背景
Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity).
Endoplasmic reticulum.
Heterodimer of a catalytic alpha subunit (GANAB) and a beta subunit (PRKCSH). Binds glycosylated PTPRC (By similarity).
研究領域
· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum. (View pathway)
Restrictive clause
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