CKMT2 Antibody - #DF3104
| 製品: | CKMT2 Antibody |
| カタログ: | DF3104 |
| タンパク質の説明: | Rabbit polyclonal antibody to CKMT2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 48 KD; 48kD(Calculated). |
| ユニプロット: | P17540 |
| RRID: | AB_2835481 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3104, RRID:AB_2835481.
折りたたみ／展開
CKMT 2; Basic-type mitochondrial creatine kinase; CKMT2; CPK; Creatine kinase mitochondrial 2; Creatine kinase mitochondrial 2 (sarcomeric); Creatine kinase S-type; creatine kinase S-type, mitochondrial; Creatine kinase, sarcomeric mitochondrial; KCRS_HUMAN; Mib CK; Mib-CK; mitochondrial; OTTHUMP00000147542; S-MtCK; Sarcomeric mitochondrial creatine kinase; SMTCK;
免疫原
- P17540 KCRS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASIFSKLLTGRNASLLFATMGTSVLTTGYLLNRQKVCAEVREQPRLFPPSADYPDLRKHNNCMAECLTPAIYAKLRNKVTPNGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHTTDLDASKITQGQFDEHYVLSSRVRTGRSIRGLSLPPACTRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGKK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P17540 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y73 | Phosphorylation | Uniprot | |
| Y85 | Phosphorylation | Uniprot | |
| T142 | Phosphorylation | Uniprot | |
| T143 | Phosphorylation | Uniprot | |
| S148 | Phosphorylation | Uniprot | |
| T151 | Phosphorylation | Uniprot | |
| Y159 | Phosphorylation | Uniprot | |
| S162 | Phosphorylation | Uniprot | |
| S163 | Phosphorylation | Uniprot | |
| T167 | Phosphorylation | Uniprot | |
| S170 | Phosphorylation | Uniprot | |
| S175 | Phosphorylation | Uniprot | |
| Y207 | Phosphorylation | Uniprot | |
| Y208 | Phosphorylation | Uniprot | |
| S211 | Phosphorylation | Uniprot | |
| T214 | Phosphorylation | Uniprot | |
| Y255 | Phosphorylation | Uniprot | |
| K281 | Acetylation | Uniprot | |
| Y313 | Phosphorylation | Uniprot | |
| S319 | Phosphorylation | Uniprot | |
| S343 | Phosphorylation | Uniprot | |
| R350 | Methylation | Uniprot | |
| T356 | Phosphorylation | Uniprot | |
| T361 | Phosphorylation | Uniprot | |
| Y368 | Phosphorylation | Uniprot | |
| S371 | Phosphorylation | Uniprot | |
| Y393 | Phosphorylation | Uniprot | |
| K419 | Acetylation | Uniprot |
研究背景
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Mitochondrion inner membrane>Peripheral membrane protein>Intermembrane side.
Sarcomere-specific. Found only in heart and skeletal muscles.
Exists as an octamer composed of four CKMT2 homodimers.
Belongs to the ATP:guanido phosphotransferase family.
研究領域
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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