製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
Copper transport 1 homolog; Copper transporter 1; COPT1; COPT1_HUMAN; CTR1; hCTR1; High affinity copper uptake protein 1; SLC31A1; solute carrier family 31 (copper tansporters) member 1; Solute carrier family 31 member 1;
免疫原
A synthetic peptide from human SLC31A1
- O15431 COPT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDHSHHMGMSYMDSNSTMQPSHHHPTTSASHSHGGGDSSMMMMPMTFYFGFKNVELLFSGLVINTAGEMAGAFVAVFLLAMFYEGLKIARESLLRKSQVSIRYNSMPVPGPNGTILMETHKTVGQQMLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYLCIAVAAGAGTGYFLFSWKKAVVVDITEHCH
研究背景
High-affinity, saturable copper transporter involved in dietary copper uptake.
O-Glycosylation at Thr-27 protects from proteolytic cleavage in the N-terminal extracellular domain.
Cell membrane>Multi-pass membrane protein.
Note: Localizes to the apical membrane in intestinal epithelial cells.
Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
研究領域
· Human Diseases > Drug resistance: Antineoplastic > Platinum drug resistance.
· Organismal Systems > Digestive system > Mineral absorption.
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