TF2E2 Antibody - #DF3144
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3144, RRID:AB_2835521.
折りたたみ／展開
FE; General transcription factor IIE subunit 2; General transcription factor IIE, polypeptide 2, beta 34kDa; gtf2e2; T2EB_HUMAN; TF2E 2; TF2E2; TFIIE B; TFIIE-beta; Transcription initiation factor IIE beta subunit; Transcription initiation factor IIE subunit beta;
免疫原
- P29084 T2EB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDPSLLRERELFKKRALSTPVVEKRSASSESSSSSSKKKKTKVEHGGSSGSKQNSDHSNGSFNLKALSGSSGYKFGVLAKIVNYMKTRHQRGDTHPLTLDEILDETQHLDIGLKQKQWLMTEALVNNPKIEVIDGKYAFKPKYNVRDKKALLRLLDQHDQRGLGGILLEDIEEALPNSQKAVKALGDQILFVNRPDKKKILFFNDKSCQFSVDEEFQKLWRSVTVDSMDEEKIEEYLKRQGISSMQESGPKKVAPIQRRKKPASQKKRRFKTHNEHLAGVLKDYSDITSSK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P29084 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| S18 | Phosphorylation | Uniprot | |
| T19 | Phosphorylation | Uniprot | |
| K24 | Acetylation | Uniprot | |
| S26 | Phosphorylation | Uniprot | |
| S29 | Phosphorylation | Uniprot | |
| S35 | Phosphorylation | Uniprot | |
| S36 | Phosphorylation | Uniprot | |
| K52 | Acetylation | Uniprot | |
| S58 | Phosphorylation | Uniprot | |
| S61 | Phosphorylation | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| T87 | Phosphorylation | Uniprot | |
| K114 | Ubiquitination | Uniprot | |
| K116 | Acetylation | Uniprot | |
| T121 | Phosphorylation | Uniprot | |
| K129 | Acetylation | Uniprot | |
| K180 | Ubiquitination | Uniprot | |
| K183 | Ubiquitination | Uniprot | |
| K198 | Acetylation | Uniprot | |
| K206 | Acetylation | Uniprot | |
| K218 | Ubiquitination | Uniprot | |
| S227 | Phosphorylation | Uniprot | |
| K238 | Methylation | Uniprot | |
| K238 | Ubiquitination | Uniprot | |
| S264 | Phosphorylation | Uniprot | |
| K271 | Ubiquitination | Uniprot | |
| K282 | Ubiquitination | Uniprot | |
| Y284 | Phosphorylation | Uniprot |
研究背景
Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Nucleus.
Tetramer of two alpha and two beta chains. Interacts with FACT subunit SUPT16H. Interacts with ATF7IP. Interacts with SND1.
Belongs to the TFIIE beta subunit family.
研究領域
· Genetic Information Processing > Transcription > Basal transcription factors.
· Human Diseases > Infectious diseases: Viral > Epstein-Barr virus infection.
· Human Diseases > Cancers: Overview > Viral carcinogenesis.
Restrictive clause
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For Research Use Only.
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