p53 Recombinant Rabbit mAb - #BF3878
製品説明
ソース:
Rabbit IgG
アプリケーション:
WB 1:1000, IF/ICC 1:100-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human, Mouse
クローナリティ:
Monoclonal [ReFirm23325]
特異性:
p53 Recombinant Rabbit mAb detects endogenous levels of p53.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
Antigen NY-CO-13; BCC7; Cellular tumor antigen p53; FLJ92943; LFS1; Mutant tumor protein 53; p53; p53 tumor suppressor; P53_HUMAN; Phosphoprotein p53; Tp53; Transformation related protein 53; TRP53; Tumor protein 53; Tumor protein p53; Tumor suppressor p53;
免疫原
免疫原:
A synthetic peptide from mouse p53
遺伝子(ID):
タンパク質の説明:
This gene encodes a tumor suppressor protein containing transcriptional activation,DNA binding,and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes,thereby inducing cell cycle arrest,apoptosis,senescence,DNA repair,or changes in metabolism. Mutations in this gene are associated with a variety of human cancers,including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546,20937277).
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