製品: ADK Antibody
カタログ: DF3218
タンパク質の説明: Rabbit polyclonal antibody to ADK
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 40 KD; 41kD(Calculated).
ユニプロット: P55263
RRID: AB_2835598

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(92%), Sheep(100%), Rabbit(92%), Dog(100%), Chicken(92%), Xenopus(83%)
クローナリティ:
Polyclonal
特異性:
ADK Antibody detects endogenous levels of total ADK.
RRID:
AB_2835598
引用形式: Affinity Biosciences Cat# DF3218, RRID:AB_2835598.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

2310026J05Rik; 5033405D03Rik; Adenosine 5''-phosphotransferase; Adenosine kinase; adk; ADK_HUMAN; AI255373; AI987814; AK; MGC6593; OTTHUMP00000019864; OTTHUMP00000019865;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P55263 ADK_HUMAN:

Widely expressed. Highest level in placenta, liver, muscle and kidney.

タンパク質配列:
MAAAEEEPKPKKLKVEAPQALRENILFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEDKHKELFDELVKKFKVEYHAGGSTQNSIKVAQWMIQQPHKAATFFGCIGIDKFGEILKRKAAEAHVDAHYYEQNEQPTGTCAACITGDNRSLIANLAAANCYKKEKHLDLEKNWMLVEKARVCYIAGFFLTVSPESVLKVAHHASENNRIFTLNLSAPFISQFYKESLMKVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGDAFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Horse
92
Chicken
92
Rabbit
92
Xenopus
83
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P55263 基板として

Site PTM Type Enzyme
A2 Acetylation
K42 Ubiquitination
K47 Acetylation
K47 Ubiquitination
K51 Ubiquitination
K61 Ubiquitination
K63 Ubiquitination
K71 Ubiquitination
Y77 Phosphorylation
K111 Ubiquitination
K117 Ubiquitination
C160 S-Nitrosylation
K162 Acetylation
K162 Sumoylation
K162 Ubiquitination
K165 Ubiquitination
K171 Ubiquitination
T246 Phosphorylation
K256 Ubiquitination
K259 Ubiquitination
K264 Ubiquitination
K270 Acetylation
K274 Acetylation
C353 S-Nitrosylation

研究背景

機能:

ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.

細胞の位置付け:

Nucleus.

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Widely expressed. Highest level in placenta, liver, muscle and kidney.

サブユニット構造:

Monomer.

タンパク質ファミリー:

Belongs to the carbohydrate kinase PfkB family.

研究領域

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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