CKS1 Antibody - #DF3221
(1)
(6)
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3221, RRID:AB_2835601.
折りたたみ／展開
CDC2 associated protein CKS1; CDC28 protein kinase 1; CDC28 protein kinase 1B; CDC28 protein kinase regulatory subunit 1B; Cell division control protein CKS1; CKS 1; CKS-1; CKS1; CKS1_HUMAN; Cks1b; Ckshs1; Cyclin dependent kinases regulatory subunit 1; Cyclin-dependent kinases regulatory subunit 1; NB4 apoptosis/differentiation related protein; PNAS 143; PNAS 16; PNAS 18;
免疫原
- P61024 CKS1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSHKQIYYSDKYDDEEFEYRHVMLPKDIAKLVPKTHLMSESEWRNLGVQQSQGWVHYMIHEPEPHILLFRRPLPKKPKK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P61024 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| K4 | Ubiquitination | Uniprot | |
| Y7 | Phosphorylation | Uniprot | |
| Y8 | Phosphorylation | Uniprot | |
| S9 | Phosphorylation | Uniprot | |
| K11 | Ubiquitination | Uniprot | |
| Y12 | Phosphorylation | Uniprot | |
| Y19 | Phosphorylation | Uniprot | |
| K26 | Ubiquitination | Uniprot | |
| K30 | Ubiquitination | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| S39 | Phosphorylation | Uniprot | |
| S41 | Phosphorylation | Uniprot | |
| S51 | Phosphorylation | Uniprot | |
| Y57 | Phosphorylation | Uniprot |
研究背景
Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
Forms a homohexamer that can probably bind six kinase subunits.
Belongs to the CKS family.
研究領域
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Human Diseases > Cancers: Specific types > Small cell lung cancer. (View pathway)
参考文献
Application: WB Species: Human Sample: PC cells
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