MEF2B Antibody - #DF3236
| 製品: | MEF2B Antibody |
| カタログ: | DF3236 |
| タンパク質の説明: | Rabbit polyclonal antibody to MEF2B |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 予測: | Pig, Bovine, Horse, Sheep, Dog |
| 分子量: | 38 KD; 39kD(Calculated). |
| ユニプロット: | Q02080 |
| RRID: | AB_2835616 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3236, RRID:AB_2835616.
折りたたみ／展開
MADS box transcription enhancer factor 2; MDS1 EVI1; Mef2b; MEF2B_HUMAN; Myocyte enhancer factor 2B; Myocyte specific enhancer factor 2B; Myocyte-specific enhancer factor 2B; PRDM3; RSRFR2; Serum response factor like protein 2; Serum response factor-like protein 2; XMEF2;
免疫原
- Q02080 MEF2B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGRKKIQISRILDQRNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSANRLFQYASTDMDRVLLKYTEYSEPHESRTNTDILETLKRRGIGLDGPELEPDEGPEEPGEKFRRLAGEGGDPALPRPRLYPAAPAMPSPDVVYGALPPPGCDPSGLGEALPAQSRPSPFRPAAPKAGPPGLVHPLFSPSHLTSKTPPPLYLPTEGRRSDLPGGLAGPRGGLNTSRSLYSGLQNPCSTATPGPPLGSFPFLPGGPPVGAEAWARRVPQPAAPPRRPPQSASSLSASLRPPGAPATFLRPSPIPCSSPGPWQSLCGLGPPCAGCPWPTAGPGRRSPGGTSPERSPGTARARGDPTSLQASSEKTQQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q02080 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K23 | Ubiquitination | Uniprot | |
| K89 | Ubiquitination | Uniprot | |
| K112 | Ubiquitination | Uniprot | |
| T196 | Phosphorylation | Uniprot |
研究背景
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.
Nucleus.
Expressed in skeletal and cardiac muscle and brain.
Interacts with HDAC7 (By similarity). Heterodimer. Interacts with HDAC9.
Belongs to the MEF2 family.
研究領域
· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Apelin signaling pathway. (View pathway)
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