MVK Antibody - #DF3238
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3238, RRID:AB_2835618.
折りたたみ／展開
FLJ96772; KIME_HUMAN; LH receptor mRNA binding protein; LRBP; Mevalonate kinase 1; Mevalonate kinase; Mevalonic aciduria; MK; mvk; MVLK; POROK3;
免疫原
- Q03426 KIME_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q03426 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T37 | Phosphorylation | Uniprot | |
| S45 | Phosphorylation | Uniprot | |
| K59 | Ubiquitination | Uniprot | |
| K90 | Ubiquitination | Uniprot | |
| K179 | Ubiquitination | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| S227 | Phosphorylation | Uniprot | |
| K238 | Ubiquitination | Uniprot | |
| K330 | Ubiquitination | Uniprot | |
| K345 | Ubiquitination | Uniprot |
研究背景
Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
Cytoplasm. Peroxisome.
Homodimer.
Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
研究領域
· Cellular Processes > Transport and catabolism > Peroxisome. (View pathway)
· Metabolism > Metabolism of terpenoids and polyketides > Terpenoid backbone biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
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