TNFC Antibody - #DF3243
| 製品: | TNFC Antibody |
| カタログ: | DF3243 |
| タンパク質の説明: | Rabbit polyclonal antibody to TNFC |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 22 KD; 25kD(Calculated). |
| ユニプロット: | Q06643 |
| RRID: | AB_2835623 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3243, RRID:AB_2835623.
折りたたみ／展開
LT beta; LT-beta; Ltb; lymphotoxin beta; Lymphotoxin-beta; p33; TNF-C; TNFC; TNFC_HUMAN; TNFSF3; Tumor necrosis factor C; Tumor necrosis factor ligand superfamily member 3;
免疫原
- Q06643 TNFC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGALGLEGRGGRLQGRGSLLLAVAGATSLVTLLLAVPITVLAVLALVPQDQGGLVTETADPGAQAQQGLGFQKLPEEEPETDLSPGLPAAHLIGAPLKGQGLGWETTKEQAFLTSGTQFSDAEGLALPQDGLYYLYCLVGYRGRAPPGGGDPQGRSVTLRSSLYRAGGAYGPGTPELLLEGAETVTPVLDPARRQGYGPLWYTSVGFGGLVQLRRGERVYVNISHPDMVDFARGKTFFGAVMVG
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.
Membrane>Single-pass type II membrane protein.
Spleen and thymus.
Heterotrimer of either two LTB and one LTA subunits or (less prevalent) one LTB and two LTA subunits.
Belongs to the tumor necrosis factor family.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
· Environmental Information Processing > Signal transduction > NF-kappa B signaling pathway. (View pathway)
· Human Diseases > Immune diseases > Rheumatoid arthritis.
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