SFRS4 Antibody - #DF3245
| 製品: | SFRS4 Antibody |
| カタログ: | DF3245 |
| タンパク質の説明: | Rabbit polyclonal antibody to SFRS4 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 予測: | Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 57 KD; 57kD(Calculated). |
| ユニプロット: | Q08170 |
| RRID: | AB_2835625 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3245, RRID:AB_2835625.
折りたたみ／展開
arginine/serine-rich 4; Pre mRNA splicing factor SRP75; Pre-mRNA-splicing factor SRP75; Serine/arginine-rich splicing factor 4; Splicing factor; Splicing factor, arginine/serine rich 4; Splicing factor, arginine/serine rich, 75-KD; SRP001LB; SRP75; Srsf4; SRSF4_HUMAN;
免疫原
- Q08170 SRSF4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q08170 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R8 | Methylation | Uniprot | |
| K23 | Ubiquitination | Uniprot | |
| K27 | Ubiquitination | Uniprot | |
| Y53 | Phosphorylation | Uniprot | |
| K58 | Ubiquitination | Uniprot | |
| R71 | Methylation | Uniprot | |
| S78 | Phosphorylation | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| R83 | Methylation | Uniprot | |
| S84 | Phosphorylation | Uniprot | |
| S112 | Phosphorylation | Uniprot | |
| S113 | Phosphorylation | Uniprot | |
| S116 | Phosphorylation | Uniprot | |
| T131 | Phosphorylation | Uniprot | |
| Y132 | Phosphorylation | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| K154 | Acetylation | Uniprot | |
| K159 | Ubiquitination | Uniprot | |
| K176 | Acetylation | Uniprot | |
| S179 | Phosphorylation | Uniprot | |
| S186 | Phosphorylation | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| S190 | Phosphorylation | Uniprot | |
| S192 | Phosphorylation | Uniprot | |
| S222 | Phosphorylation | Uniprot | |
| S232 | Phosphorylation | Uniprot | |
| S238 | Phosphorylation | Uniprot | |
| S255 | Phosphorylation | Uniprot | |
| S257 | Phosphorylation | Uniprot | |
| S259 | Phosphorylation | Uniprot | |
| K264 | Acetylation | Uniprot | |
| S265 | Phosphorylation | Uniprot | |
| S267 | Phosphorylation | Uniprot | |
| S269 | Phosphorylation | Uniprot | |
| K287 | Acetylation | Uniprot | |
| S288 | Phosphorylation | Uniprot | |
| S290 | Phosphorylation | Uniprot | |
| S292 | Phosphorylation | Uniprot | |
| S300 | Phosphorylation | Uniprot | |
| S302 | Phosphorylation | Uniprot | |
| S304 | Phosphorylation | Uniprot | |
| S316 | Phosphorylation | Uniprot | |
| S318 | Phosphorylation | Uniprot | |
| S322 | Phosphorylation | Uniprot | |
| S360 | Phosphorylation | Uniprot | |
| S364 | Phosphorylation | Uniprot | |
| S368 | Phosphorylation | Uniprot | |
| S410 | Phosphorylation | Uniprot | |
| S412 | Phosphorylation | Uniprot | |
| S420 | Phosphorylation | Uniprot | |
| R428 | Methylation | Uniprot | |
| S431 | Phosphorylation | Uniprot | |
| T436 | Phosphorylation | Uniprot | |
| T440 | Phosphorylation | Uniprot | |
| S442 | Phosphorylation | Uniprot | |
| S446 | Phosphorylation | Uniprot | |
| S448 | Phosphorylation | Uniprot | |
| S450 | Phosphorylation | Uniprot | |
| S456 | Phosphorylation | Uniprot | |
| S458 | Phosphorylation | Uniprot | |
| S460 | Phosphorylation | Uniprot | |
| S462 | Phosphorylation | Uniprot |
研究背景
Plays a role in alternative splice site selection during pre-mRNA splicing. Represses the splicing of MAPT/Tau exon 10.
Extensively phosphorylated on serine residues in the RS domain.
Nucleus speckle.
Found in a pre-mRNA splicing complex with SRSF4/SFRS4, SRSF5/SFRS5, SNRNP70, SNRPA1, SRRM1 and SRRM2. Interacts with PNN.
Belongs to the splicing factor SR family.
研究領域
· Genetic Information Processing > Transcription > Spliceosome.
· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.
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