Carbonic Anhydrase 1/CA1 Recombinant Rabbit mAb - #BF4579

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製品: Carbonic Anhydrase 1/CA1 Recombinant Rabbit mAb
カタログ: BF4579
タンパク質の説明: Rabbit monoclonal antibody to Carbonic Anhydrase 1/CA1
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
分子量: 29 kDa(Observed); 29kD(Calculated).
ユニプロット: P00915

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製品説明

ソース:
Rabbit IgG
アプリケーション:
WB 1:1000, IHC 1:200-1:2000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human, Mouse, Rat
クローナリティ:
Monoclonal [ReFirm24029]
特異性:
Carbonic Anhydrase 1/CA1 Recombinant Rabbit mAb detects endogenous levels of Carbonic Anhydrase 1/CA1.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

CA 1; CA I; CA-I; CA1; CAB; CAH1_HUMAN; CAI; CAN; Car 1; Car1; Carbonate dehydratase I; Carbonic anhydrase 1; Carbonic anhydrase A; Carbonic anhydrase B; Carbonic anhydrase B, formerly; Carbonic anhydrase I; Carbonic dehydratase; ECK0125; JW0122; yadF;

免疫原

免疫原:

A synthetic peptide from human Carbonic Anhydrase 1

Uniprot:

P00915(CAH1_HUMAN) >>Visit HPA database.

遺伝子(ID):
CA1(759)
タンパク質の説明:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes,including respiration,calcification,acid-base balance,bone resorption,and the formation of aqueous humor,cerebrospinal fluid,saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
タンパク質配列:
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF

研究背景

機能:

Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the alpha-carbonic anhydrase family.

研究領域

· Metabolism > Energy metabolism > Nitrogen metabolism.

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