CNKR2 Antibody - #DF3375
(1)
| 製品: | CNKR2 Antibody |
| カタログ: | DF3375 |
| タンパク質の説明: | Rabbit polyclonal antibody to CNKR2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 117 KD; 118kD(Calculated). |
| ユニプロット: | Q8WXI2 |
| RRID: | AB_2835757 |
製品説明
ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(83%)
クローナリティ:
Polyclonal
特異性:
CNKR2 Antibody detects endogenous levels of total CNKR2.
RRID:
AB_2835757
引用形式: Affinity Biosciences Cat# DF3375, RRID:AB_2835757.
引用形式: Affinity Biosciences Cat# DF3375, RRID:AB_2835757.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
CNK2; CNKSR2; Connector enhancer of kinase suppressor of Ras 2; Connector enhancer of KSR2; KIAA0902; KSR2; RP11 450P7.2;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
- Q8WXI2 CNKR2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALIMEPVSKWSPSQVVDWMKGLDDCLQQYIKNFEREKISGDQLLRITHQELEDLGVSRIGHQELILEAVDLLCALNYGLETENLKTLSHKLNASAKNLQNFITGRRRSGHYDGRTSRKLPNDFLTSVVDLIGAAKSLLAWLDRSPFAAVTDYSVTRNNVIQLCLELTTIVQQDCTVYETENKILHVCKTLSGVCDHIISLSSDPLVSQSAHLEVIQLANIKPSEGLGMYIKSTYDGLHVITGTTENSPADRCKKIHAGDEVIQVNHQTVVGWQLKNLVNALREDPSGVILTLKKRPQSMLTSAPALLKNMRWKPLALQPLIPRSPTSSVATPSSTISTPTKRDSSALQDLYIPPPPAEPYIPRDEKGNLPCEDLRGHMVGKPVHKGSESPNSFLDQEYRKRFNIVEEDTVLYCYEYEKGRSSSQGRRESTPTYGKLRPISMPVEYNWVGDYEDPNKMKRDSRRENSLLRYMSNEKIAQEEYMFQRNSKKDTGKKSKKKGDKSNSPTHYSLLPSLQMDALRQDIMGTPVPETTLYHTFQQSSLQHKSKKKNKGPIAGKSKRRISCKDLGRGDCEGWLWKKKDAKSYFSQKWKKYWFVLKDASLYWYINEEDEKAEGFISLPEFKIDRASECRKKYAFKACHPKIKSFYFAAEHLDDMNRWLNRINMLTAGYAERERIKQEQDYWSESDKEEADTPSTPKQDSPPPPYDTYPRPPSMSCASPYVEAKHSRLSSTETSQSQSSHEEFRQEVTGSSAVSPIRKTASQRRSWQDLIETPLTSSGLHYLQTLPLEDSVFSDSAAISPEHRRQSTLPTQKCHLQDHYGPYPLAESERMQVLNGNGGKPRSFTLPRDSGFNHCCLNAPVSACDPQDDVQPPEVEEEEEEEEEEGEAAGENIGEKSESREEKLGDSLQDLYRALEQASLSPLGEHRISTKMEYKLSFIKRCNDPVMNEKLHRLRILKSTLKAREGEVAIIDKVLDNPDLTSKEFQQWKQMYLDLFLDICQNTTSNDPLSISSEVDVITSSLAHTHSYIETHV
種類予測
種類予測:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
83
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8WXI2 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T292 | Phosphorylation | Uniprot | |
| S303 | Phosphorylation | Uniprot | |
| S325 | Phosphorylation | Uniprot | |
| S388 | Phosphorylation | Uniprot | |
| S390 | Phosphorylation | Uniprot | |
| T433 | Phosphorylation | Uniprot | |
| Y434 | Phosphorylation | Uniprot | |
| Y452 | Phosphorylation | Uniprot | |
| S467 | Phosphorylation | Uniprot | |
| S473 | Phosphorylation | Uniprot | |
| S564 | Phosphorylation | Uniprot | |
| T694 | Phosphorylation | Uniprot | |
| S756 | Phosphorylation | Uniprot | |
| S808 | Phosphorylation | Uniprot | |
| Y821 | Phosphorylation | Uniprot | |
| S908 | Phosphorylation | Uniprot |
研究背景
機能:
May function as an adapter protein or regulator of Ras signaling pathways.
PTMs:
Phosphorylated on tyrosine.
細胞の位置付け:
Cytoplasm. Membrane>Peripheral membrane protein.
サブユニット構造:
Interacts with RAF1, RAB2L and RAL GTPase proteins.
タンパク質ファミリー:
Belongs to the CNKSR family.
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