DLX4 Antibody - #DF3387

(1)   (2)  
製品: DLX4 Antibody
カタログ: DF3387
タンパク質の説明: Rabbit polyclonal antibody to DLX4
アプリケーション: WB IF/ICC
反応性: Human
予測: Bovine, Sheep, Dog
分子量: 34 KD; 26kD(Calculated).
ユニプロット: Q92988
RRID: AB_2835769

類似製品を見る>>

   サイズ 価格 在庫状況
 100ul $280 在庫あり
 200ul $350 在庫あり

リードタイム: 当日配達

For pricing and ordering contact:
お問い合わせ先
関連ダウンロード
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Bovine(88%), Sheep(88%), Dog(88%)
クローナリティ:
Polyclonal
特異性:
DLX4 Antibody detects endogenous levels of total DLX4.
RRID:
AB_2835769
引用形式: Affinity Biosciences Cat# DF3387, RRID:AB_2835769.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Beta protein 1; BP1; Distal less homeo box 7; Distal less homeo box 9; distal-less homeobox 4; DLX4; DLX4_HUMAN; DLX7; DLX8; DLX9; Homeobox protein DLX-4; Homeobox protein DLX-7; Homeobox protein DLX-8; Homeobox protein DLX4;

免疫原

免疫原:
Uniprot:

Q92988(DLX4_HUMAN) >>Visit HPA database.

遺伝子(ID):
DLX4(1748)
発現特異性:
Q92988 DLX4_HUMAN:

Expressed in leukemia cells and placenta. Also expressed in kidney and fetal liver.

タンパク質配列:
MTSLPCPLPGRDASKAVFPDLAPVPSVAAAYPLGLSPTTAASPNLSYSRPYGHLLSYPYTEPANPGDSYLSCQQPAALSQPLCGPAEHPQELEADSEKPRLSPEPSERRPQAPAKKLRKPRTIYSSLQLQHLNQRFQHTQYLALPERAQLAAQLGLTQTQVKIWFQNKRSKYKKLLKQNSGGQEGDFPGRTFSVSPCSPPLPSLWDLPKAGTLPTSGYGNSFGAWYQHHSSDVLASPQMM

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
88
Sheep
88
Dog
88
Pig
0
Horse
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q92988 基板として

Site PTM Type Enzyme
T2 Phosphorylation
S3 Phosphorylation
S14 Phosphorylation
S96 Phosphorylation
S198 Phosphorylation

研究背景

機能:

May play a role in determining the production of hemoglobin S. May act as a repressor. During embryonic development, plays a role in palatogenesis.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in leukemia cells and placenta. Also expressed in kidney and fetal liver.

タンパク質ファミリー:

Belongs to the distal-less homeobox family.

参考文献

1). Identification and validation of DLX4 as a prognostic and diagnostic biomarker for clear cell renal cell carcinoma. Oncology Letters, 2023 (PubMed: 36936018) [IF=2.9]

Application: IHC    Species: Human    Sample: ccRCC tissues

Figure 5. High expression levels of DLX4 in ccRCC tissues. (A and B) Reverse transcription-quantitative PCR revealed high expression levels of DLX4 mRNA in ccRCC tissues compared with normal adjacent tissue. (C and D) Immunohistochemistry showed high expression levels of DLX4 protein in ccRCC tissues compared with normal adjacent tissue. Scale bar for entire images and local magnification images were 100 and 50 µm, respectively. ccRCC, clear cell renal cell carcinoma; DLX, distal-less homeobox. **P

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.