製品: DUSP9 Antibody
カタログ: DF3413
タンパク質の説明: Rabbit polyclonal antibody to DUSP9
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Rabbit
分子量: 42 KD; 42kD(Calculated).
ユニプロット: Q99956
RRID: AB_2835795

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(89%), Rabbit(89%)
クローナリティ:
Polyclonal
特異性:
DUSP9 Antibody detects endogenous levels of total DUSP9.
RRID:
AB_2835795
引用形式: Affinity Biosciences Cat# DF3413, RRID:AB_2835795.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Dual specificity phosphatase 9; Dual specificity protein phosphatase 9; DUS9_HUMAN; DUSP9; MAP kinase phosphatase 4; Mitogen activated protein kinase phosphatase 4; Mitogen-activated protein kinase phosphatase 4; MKP 4; MKP-4; MKP4; serine/threonine specific protein phosphatase;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPALLLRRLRRGSLSVRALLPGPPLQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLGSLCLGSDCSDAESEADRDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFERSLRLEERHSQEQGSGGQASAASNPPSFFTTPTSDGAFELAPT

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
89
Pig
89
Horse
78
Dog
78
Bovine
67
Sheep
67
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q99956 基板として

Site PTM Type Enzyme
S16 Phosphorylation
S58 Phosphorylation
T193 Phosphorylation
S219 Phosphorylation
Y232 Phosphorylation
T237 Phosphorylation
S262 Phosphorylation
K324 Ubiquitination
S325 Phosphorylation
S328 Phosphorylation
S351 Phosphorylation
S356 Phosphorylation
S361 Phosphorylation
T372 Phosphorylation
T374 Phosphorylation
S375 Phosphorylation

研究背景

機能:

Inactivates MAP kinases. Has a specificity for the ERK family.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

研究領域

· Cellular Processes > Cellular community - eukaryotes > Signaling pathways regulating pluripotency of stem cells.   (View pathway)

· Environmental Information Processing > Signal transduction > MAPK signaling pathway.   (View pathway)

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