ARNT2 Antibody - #DF3441
| 製品: | ARNT2 Antibody |
| カタログ: | DF3441 |
| タンパク質の説明: | Rabbit polyclonal antibody to ARNT2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Horse, Sheep, Dog, Chicken, Xenopus |
| 分子量: | 79 KD; 79kD(Calculated). |
| ユニプロット: | Q9HBZ2 |
| RRID: | AB_2835807 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3441, RRID:AB_2835807.
折りたたみ／展開
ARNT protein 2; ARNT2; ARNT2_HUMAN; Aryl hydrocarbon receptor nuclear translocator 2; bHLHe1; Class E basic helix-loop-helix protein 1;
免疫原
- Q9HBZ2 ARNT2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATPAAVNPPEMASDIPGSVTLPVAPMAATGQVRMAGAMPARGGKRRSGMDFDDEDGEGPSKFSRENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMTIPEEDADVGQGSKYCLVAIGRLQVTSSPVCMDMNGMSVPTEFLSRHNSDGIITFVDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWMLIRTSSFTFQNPYSDEIEYIICTNTNVKQLQQQQAELEVHQRDGLSSYDLSQVPVPNLPAGVHEAGKSVEKADAIFSQERDPRFAEMFAGISASEKKMMSSASAAGTQQIYSQGSPFPSGHSGKAFSSSVVHVPGVNDIQSSSSTGQNMSQISRQLNQSQVAWTGSRPPFPGQQIPSQSSKTQSSPFGIGTSHTYPADPSSYSPLSSPATSSPSGNAYSSLANRTPGFAESGQSSGQFQGRPSEVWSQWQSQHHGQQSGEQHSHQQPGQTEVFQDMLPMPGDPTQGTGNYNIEDFADLGMFPPFSE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9HBZ2 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R42 | Methylation | Uniprot | |
| S94 | Phosphorylation | Uniprot | |
| K214 | Ubiquitination | Uniprot | |
| K507 | Acetylation | Uniprot | |
| S540 | Phosphorylation | Uniprot | |
| R578 | Methylation | Uniprot | |
| S588 | Phosphorylation | Uniprot | |
| S614 | Phosphorylation | Uniprot | |
| T621 | Phosphorylation | Uniprot |
研究背景
Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function. Specifically recognizes the xenobiotic response element (XRE).
Nucleus.
Efficient DNA binding requires dimerization with another bHLH protein (By similarity). Heterodimer with NPAS4. Heterodimer with SIM1 (By similarity). Heterodimer with the aryl hydrocarbon receptor (AHR) or the SIM1 protein (By similarity). Interacts with TACC3 (By similarity).
研究領域
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.
· Human Diseases > Cancers: Specific types > Renal cell carcinoma. (View pathway)
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