HMG20B Antibody - #DF3458
| 製品: | HMG20B Antibody |
| カタログ: | DF3458 |
| タンパク質の説明: | Rabbit polyclonal antibody to HMG20B |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human |
| 予測: | Pig, Zebrafish, Bovine, Sheep, Dog, Xenopus |
| 分子量: | 36 KD; 36kD(Calculated). |
| ユニプロット: | Q9P0W2 |
| RRID: | AB_2835823 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3458, RRID:AB_2835823.
折りたたみ／展開
BRAF25; BRAF35; BRCA2 associated factor 35; BRCA2-associated factor 35; High Mobility Group Protein 20B; HM20B_HUMAN; HMG box containing protein 20B; HMG box-containing protein 20B; HMG domain-containing protein 2; HMG domain-containing protein HMGX2; HMG20B; SMARCE1-related protein; SMARCE1r; sox like; Sox like transcriptional factor; Sox-like transcriptional factor; SOXL; Structural DNA binding protein BRAF35; Structural DNA-binding protein BRAF35; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related;
免疫原
- Q9P0W2 HM20B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSHGPKQPGAAAAPAGGKAPGQHGGFVVTVKQERGEGPRAGEKGSHEEEPVKKRGWPKGKKRKKILPNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKMLGAEWSKLQPTEKQRYLDEAEREKQQYMKELRAYQQSEAYKMCTEKIQEKKIKKEDSSSGLMNTLLNGHKGGDCDGFSTFDVPIFTEEFLDQNKAREAELRRLRKMNVAFEEQNAVLQRHTQSMSSARERLEQELALEERRTLALQQQLQAVRQALTASFASLPVPGTGETPTLGTLDFYMARLHGAIERDPAQHEKLIVRIKEILAQVASEHL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9P0W2 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| K6 | Sumoylation | Uniprot | |
| K31 | Acetylation | Uniprot | |
| K31 | Sumoylation | Uniprot | |
| K71 | Sumoylation | Uniprot | |
| K110 | Sumoylation | Uniprot | |
| K110 | Ubiquitination | Uniprot | |
| K116 | Ubiquitination | Uniprot | |
| K132 | Ubiquitination | Uniprot | |
| Y143 | Phosphorylation | Uniprot | |
| K144 | Ubiquitination | Uniprot | |
| K149 | Ubiquitination | Uniprot | |
| S160 | Phosphorylation | Uniprot | |
| T167 | Phosphorylation | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| K208 | Sumoylation | Uniprot | |
| K208 | Ubiquitination | Uniprot | |
| K300 | Ubiquitination | Uniprot |
研究背景
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
Nucleus. Chromosome.
Note: Localized to condensed chromosomes in mitosis in conjunction with BRCA2.
Ubiquitously expressed in adult tissues.
Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, KDM1A, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. Interacts with the BRCA2 tumor suppressor protein.
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