製品: MOS Antibody
カタログ: AF0355
タンパク質の説明: Rabbit polyclonal antibody to MOS
アプリケーション: WB IF/ICC
反応性: Human, Monkey
予測: Pig, Zebrafish, Bovine, Dog, Chicken, Xenopus
分子量: 40kDa; 38kD(Calculated).
ユニプロット: P00540
RRID: AB_2833521

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Monkey
予測:
Pig(91%), Zebrafish(88%), Bovine(82%), Dog(91%), Chicken(91%), Xenopus(82%)
クローナリティ:
Polyclonal
特異性:
MOS Antibody detects endogenous levels of total MOS.
RRID:
AB_2833521
引用形式: Affinity Biosciences Cat# AF0355, RRID:AB_2833521.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

c mos; MGC119962; MGC119963; MOS; MOS_HUMAN; MSV; Oocyte maturation factor mos; Proto oncogene serine / threonine protein kinase mos; Proto-oncogene c-Mos; Proto-oncogene serine/threonine-protein kinase mos; v mos Moloney murine sarcoma viral oncogene homolog;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P00540 MOS_HUMAN:

Expressed specifically in testis during spermatogenesis.

タンパク質の説明:
Mos a proto-oncogenic serine/threonine kinase of the MOS family. Expressed predominantly in germ cells. Crucial for normal oocyte meiosis and female fertility in mice.
タンパク質配列:
MPSPLALRPYLRSEFSPSVDARPCSSPSELPAKLLLGATLPRAPRLPRRLAWCSIDWEQVCLLQRLGAGGFGSVYKATYRGVPVAIKQVNKCTKNRLASRRSFWAELNVARLRHDNIVRVVAASTRTPAGSNSLGTIIMEFGGNVTLHQVIYGAAGHPEGDAGEPHCRTGGQLSLGKCLKYSLDVVNGLLFLHSQSIVHLDLKPANILISEQDVCKISDFGCSEKLEDLLCFQTPSYPLGGTYTHRAPELLKGEGVTPKADIYSFAITLWQMTTKQAPYSGERQHILYAVVAYDLRPSLSAAVFEDSLPGQRLGDVIQRCWRPSAAQRPSARLLLVDLTSLKAELG

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
91
Dog
91
Chicken
91
Zebrafish
88
Bovine
82
Xenopus
82
Horse
0
Sheep
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P00540 基板として

Site PTM Type Enzyme
S3 Phosphorylation
S16 Phosphorylation
Y263 Phosphorylation
T339 Phosphorylation
S340 Phosphorylation

PTMs - P00540 酵素として

Substrate Site Source
P08670 (VIM) T458 Uniprot
P08670 (VIM) S459 Uniprot
Q02750 (MAP2K1) S218 Uniprot
Q02750 (MAP2K1) S222 Uniprot

研究背景

組織特異性:

Expressed specifically in testis during spermatogenesis.

タンパク質ファミリー:

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

研究領域

· Cellular Processes > Cell growth and death > Oocyte meiosis.   (View pathway)

· Cellular Processes > Cell motility > Regulation of actin cytoskeleton.   (View pathway)

· Organismal Systems > Endocrine system > Progesterone-mediated oocyte maturation.

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