CDH22 Antibody - #DF3529
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3529, RRID:AB_2835883.
折りたたみ／展開
C20orf25; CAD22_HUMAN; Cadherin 22, type 2; Cadherin-22; Cadherin-like 22; Cdh22; dJ998H6.1; MGC39564; Ortholog of rat PB-cadherin; PB-cadherin; Pituitary and brain cadherin;
免疫原
- Q9UJ99 CAD22_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRPRPEGRGLRAGVALSPALLLLLLLPPPPTLLGRLWAAGTPSPSAPGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGGAGGGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAALYAGHRGDDEAQAS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UJ99 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S152 | Phosphorylation | Uniprot | |
| S181 | Phosphorylation | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| Y314 | Phosphorylation | Uniprot | |
| T330 | Phosphorylation | Uniprot | |
| T331 | Phosphorylation | Uniprot | |
| S333 | Phosphorylation | Uniprot | |
| T335 | Phosphorylation | Uniprot | |
| Y430 | Phosphorylation | Uniprot | |
| S653 | Phosphorylation | Uniprot | |
| S656 | Phosphorylation | Uniprot | |
| S657 | Phosphorylation | Uniprot | |
| Y670 | Phosphorylation | Uniprot |
研究背景
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues (By similarity).
Cell membrane>Single-pass type I membrane protein.
Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.
Restrictive clause
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