製品: Cytochrome c-type Heme Lyase Antibody
カタログ: DF3540
タンパク質の説明: Rabbit polyclonal antibody to Cytochrome c-type Heme Lyase
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 31 KD; 31kD(Calculated).
ユニプロット: P53701
RRID: AB_2835913

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(91%), Bovine(91%), Horse(100%), Sheep(91%), Rabbit(91%), Dog(100%), Chicken(82%)
クローナリティ:
Polyclonal
特異性:
Cytochrome c-type Heme Lyase Antibody detects endogenous levels of total Cytochrome c-type Heme Lyase.
RRID:
AB_2835913
引用形式: Affinity Biosciences Cat# DF3540, RRID:AB_2835913.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CCHL; CCHL_HUMAN; cytochrome c heme-lyase; Cytochrome c-type heme lyase; DKFZp779I1858; EC 4.4.1.17; Hccs; Holocytochrome c synthase (cytochrome c heme lyase); Holocytochrome c synthase; Holocytochrome c type synthase; Holocytochrome c-type synthase; MCOPS7; OTTHUMP00000022903; OTTHUMP00000022904; OTTHUMP00000022905; OTTMUSP00000021173; OTTMUSP00000021174; RGD1563855; RP23-37L2.1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MGLSPSAPAVAVQASNASASPPSGCPMHEGKMKGCPVNTEPSGPTCEKKTYSVPAHQERAYEYVECPIRGTAAENKENLDPSNLMPPPNQTPAPDQPFALSTVREESSIPRADSEKKWVYPSEQMFWNAMLKKGWKWKDEDISQKDMYNIIRIHNQNNEQAWKEILKWEALHAAECPCGPSLIRFGGKAKEYSPRARIRSWMGYELPFDRHDWIINRCGTEVRYVIDYYDGGEVNKDYQFTILDVRPALDSLSAVWDRMKVAWWRWTS

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Dog
100
Pig
91
Bovine
91
Sheep
91
Rabbit
91
Chicken
82
Xenopus
64
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P53701 基板として

Site PTM Type Enzyme
G2 Myristoylation
T39 Phosphorylation
K49 Ubiquitination
Y61 Phosphorylation
Y63 Phosphorylation
K76 Ubiquitination
K136 Ubiquitination
K138 Ubiquitination
K145 Sumoylation
K145 Ubiquitination
K163 Ubiquitination
K167 Ubiquitination
S200 Phosphorylation
Y224 Phosphorylation
Y228 Phosphorylation
Y229 Phosphorylation
T241 Phosphorylation

研究背景

機能:

Links covalently the heme group to the apoprotein of cytochrome c.

細胞の位置付け:

Mitochondrion inner membrane. Membrane>Lipid-anchor.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the cytochrome c-type heme lyase family.

研究領域

· Metabolism > Metabolism of cofactors and vitamins > Porphyrin and chlorophyll metabolism.

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