Cytochrome P450 21A2 Antibody - #DF3567
| 製品: | Cytochrome P450 21A2 Antibody |
| カタログ: | DF3567 |
| タンパク質の説明: | Rabbit polyclonal antibody to Cytochrome P450 21A2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 分子量: | 55 KD; 56kD(Calculated). |
| ユニプロット: | P08686 |
| RRID: | AB_2835939 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3567, RRID:AB_2835939.
折りたたみ／展開
CYP21; 21 OHase; 21-OHase; CA21H; CAH1; CP21A_HUMAN; CPS1; CYP21A 2; CYP21A2; CYP21B; Cytochrome P-450c21; Cytochrome P450 21; Cytochrome P450 C21B; Cytochrome P450 XXI; Cytochrome P450, family 21, subfamily A, polypeptide 2; Cytochrome P450, subfamily XXIA (steroid 21 hydroxylase, congenital adrenal hyperplasia), polypeptide 2; Cytochrome P450-C21; Cytochrome P450-C21B; P450 C21; P450 C21B; P450c21B; Steroid 21 hydroxylase; Steroid 21 monooxygenase; Steroid 21-hydroxylase;
免疫原
- P08686 CP21A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLLLGLLLLPLLAGARLLWNWWKLRSLHLPPLAPGFLHLLQPDLPIYLLGLTQKFGPIYRLHLGLQDVVVLNSKRTIEEAMVKKWADFAGRPEPLTYKLVSKNYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLTQEFCERMRAQPGTPVAIEEEFSLLTCSIICYLTFGDKIKDDNLMPAYYKCIQEVLKTWSHWSIQIVDVIPFLRFFPNPGLRRLKQAIEKRDHIVEMQLRQHKESLVAGQWRDMMDYMLQGVAQPSMEEGSGQLLEGHVHMAAVDLLIGGTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDRFLEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALPSLQPLPHCSVILKMQPFQVRLQPRGMGAHSPGQNQ
PTMs - P08686 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T76 | Phosphorylation | Uniprot | |
| Y190 | Phosphorylation | Uniprot |
研究背景
Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids.
Endoplasmic reticulum membrane>Peripheral membrane protein. Microsome membrane>Peripheral membrane protein.
The leucine-rich hydrophobic amino acid N-terminal region probably helps to anchor the protein to the microsomal membrane.
Belongs to the cytochrome P450 family.
研究領域
· Metabolism > Lipid metabolism > Steroid hormone biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Endocrine system > Aldosterone synthesis and secretion.
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