製品: Cytochrome P450 26C1 Antibody
カタログ: DF3570
タンパク質の説明: Rabbit polyclonal antibody to Cytochrome P450 26C1
アプリケーション: WB IHC
反応性: Human, Mouse
予測: Pig, Bovine, Sheep, Rabbit
分子量: 0 KD; 57kD(Calculated).
ユニプロット: Q6V0L0
RRID: AB_2835942

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(82%), Bovine(91%), Sheep(91%), Rabbit(100%)
クローナリティ:
Polyclonal
特異性:
Cytochrome P450 26C1 Antibody detects endogenous levels of total Cytochrome P450 26C1.
RRID:
AB_2835942
引用形式: Affinity Biosciences Cat# DF3570, RRID:AB_2835942.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CP26C_HUMAN; cyp26b1l; CYP26C1; cyp26d1; Cytochrome P450 26C1; Cytochrome P450 family 26 subfamily C polypeptide 1; Cytochrome P450, subfamily XXVIC polypeptide 1; EG546726; FFDD4; FLJ45301; MGC158120; retinoic acid catabolizing enzyme;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q6V0L0 CP26C_HUMAN:

Detected in most tissues at very low level.

タンパク質配列:
MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVSVYDASKALTFRMAARILLGLRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRARDQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Bovine
91
Sheep
91
Pig
82
Xenopus
67
Chicken
60
Zebrafish
58
Horse
0
Dog
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q6V0L0 基板として

Site PTM Type Enzyme
Y80 Phosphorylation
S150 Phosphorylation
T300 Phosphorylation
K321 Ubiquitination

研究背景

機能:

Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).

細胞の位置付け:

Membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Detected in most tissues at very low level.

タンパク質ファミリー:

Belongs to the cytochrome P450 family.

研究領域

· Metabolism > Metabolism of cofactors and vitamins > Retinol metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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