製品: HSPB2 Antibody
カタログ: DF3601
タンパク質の説明: Rabbit polyclonal antibody to HSPB2
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Rabbit, Dog
分子量: 24 KD; 20kD(Calculated).
ユニプロット: Q16082
RRID: AB_2835973

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
HSPB2 Antibody detects endogenous levels of total HSPB2.
RRID:
AB_2835973
引用形式: Affinity Biosciences Cat# DF3601, RRID:AB_2835973.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

DMPK-binding protein; Heat shock 27kD protein 2; Heat shock 27kDa protein 2; Heat shock protein beta-2; Heat-shock protein beta-2; Hs.78846; HSP27; HspB2; HSPB2_HUMAN; LOH11CR1K; MGC133245; MKBP;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q16082 HSPB2_HUMAN:

Expressed preferentially in skeletal muscle and heart but not in the lens.

タンパク質配列:
MSGRSVPHAHPATAEYEFANPSRLGEQRFGEGLLPEEILTPTLYHGYYVRPRAAPAGEGSRAGASELRLSEGKFQAFLDVSHFTPDEVTVRTVDNLLEVSARHPQRLDRHGFVSREFCRTYVLPADVDPWRVRAALSHDGILNLEAPRGGRHLDTEVNEVYISLLPAPPDPEEEEEAAIVEP

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Dog
100
Rabbit
100
Xenopus
55
Horse
0
Sheep
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q16082 基板として

Site PTM Type Enzyme
S5 Phosphorylation
Y16 Phosphorylation
S22 Phosphorylation
Y44 Phosphorylation
R52 Methylation
S60 Phosphorylation
R61 Methylation
S65 Phosphorylation

研究背景

機能:

May regulate the kinase DMPK.

細胞の位置付け:

Cytoplasm. Nucleus.
Note: Localizes to nuclear foci.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed preferentially in skeletal muscle and heart but not in the lens.

サブユニット構造:

Interacts with DMPK; may enhance its kinase activity.

タンパク質ファミリー:

Belongs to the small heat shock protein (HSP20) family.

研究領域

· Human Diseases > Infectious diseases: Viral > Epstein-Barr virus infection.

· Human Diseases > Cancers: Overview > Proteoglycans in cancer.

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