RAD54 Antibody - #DF3631
| 製品: | RAD54 Antibody |
| カタログ: | DF3631 |
| タンパク質の説明: | Rabbit polyclonal antibody to RAD54 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 85 KD; 84kD(Calculated). |
| ユニプロット: | Q92698 |
| RRID: | AB_2836003 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3631, RRID:AB_2836003.
折りたたみ／展開
DNA repair and recombination protein RAD54 like; DNA repair and recombination protein RAD54-like; hHR 54; hHR54; HR 54; HR54; hRAD 54; hRAD54; RAD 54A; RAD 54L; RAD54 (S. cerevisiae) like; RAD54 homolog; RAD54 like (S. cerevisiae); RAD54 like; RAD54 like protein; RAD54_HUMAN; RAD54A; RAD54L;
免疫原
- Q92698 RAD54_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRRSLAPSQLAKRKPEGRSCDDEDWQPGLVTPRKRKSSSETQIQECFLSPFRKPLSQLTNQPPCLDSSQHEAFIRSILSKPFKVPIPNYQGPLGSRALGLKRAGVRRALHDPLEKDALVLYEPPPLSAHDQLKLDKEKLPVHVVVDPILSKVLRPHQREGVKFLWECVTSRRIPGSHGCIMADEMGLGKTLQCITLMWTLLRQSPECKPEIDKAVVVSPSSLVKNWYNEVGKWLGGRIQPLAIDGGSKDEIDQKLEGFMNQRGARVSSPILIISYETFRLHVGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRVLISGTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERLRELTSIVNRCLIRRTSDILSKYLPVKIEQVVCCRLTPLQTELYKRFLRQAKPAEELLEGKMSVSSLSSITSLKKLCNHPALIYDKCVEEEDGFVGALDLFPPGYSSKALEPQLSGKMLVLDYILAVTRSRSSDKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIKKRAKVVERFNSPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTCYIYRLLSAGTIEEKIFQRQSHKKALSSCVVDEEQDVERHFSLGELKELFILDEASLSDTHDRLHCRRCVNSRQIRPPPDGSDCTSDLAGWNHCTDKWGLRDEVLQAAWDAASTAITFVFHQRSHEEQRGLR
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q92698 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S4 | Phosphorylation | Uniprot | |
| K12 | Acetylation | Uniprot | |
| T31 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| S38 | Phosphorylation | Uniprot | |
| S39 | Phosphorylation | Uniprot | |
| T41 | Phosphorylation | Uniprot | |
| S49 | Phosphorylation | Uniprot | |
| K53 | Ubiquitination | Uniprot | |
| K83 | Ubiquitination | Uniprot | |
| K115 | Ubiquitination | Uniprot | |
| K133 | Ubiquitination | Uniprot | |
| K138 | Ubiquitination | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| K232 | Ubiquitination | Uniprot | |
| S247 | Phosphorylation | Uniprot | |
| K248 | Ubiquitination | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| K302 | Ubiquitination | Uniprot | |
| T308 | Phosphorylation | Uniprot | |
| Y309 | Phosphorylation | Uniprot | |
| S314 | Phosphorylation | Uniprot | |
| K355 | Ubiquitination | Uniprot | |
| K363 | Ubiquitination | Uniprot | |
| S386 | Phosphorylation | Uniprot | |
| K402 | Ubiquitination | Uniprot | |
| K407 | Ubiquitination | Uniprot | |
| K425 | Ubiquitination | Uniprot | |
| K432 | Ubiquitination | Uniprot | |
| K441 | Ubiquitination | Uniprot | |
| K454 | Ubiquitination | Uniprot | |
| K455 | Ubiquitination | Uniprot | |
| Y503 | Phosphorylation | Uniprot | |
| S572 | Phosphorylation | Uniprot | |
| K630 | Ubiquitination | Uniprot | |
| K639 | Ubiquitination | Uniprot | |
| K662 | Ubiquitination | Uniprot | |
| S671 | Phosphorylation | Uniprot |
研究背景
Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments (By similarity). May play also an essential role in telomere length maintenance and telomere capping in mammalian cells.
Nucleus.
Interacts (via N-terminus) with RAD51.
Belongs to the SNF2/RAD54 helicase family.
研究領域
· Genetic Information Processing > Replication and repair > Homologous recombination.
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