EFTUD2 Antibody - #DF3639
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3639, RRID:AB_2836011.
折りたたみ／展開
116 kDa; 116 kDa U5 small nuclear ribonucleoprotein component; EFTUD2; Elongation factor Tu GTP binding domain containing 2; Elongation factor Tu GTP-binding domain-containing protein 2; hSNU114; MFDGA; MFDM; SNRNP116; Snrp116; Snu114; SNU114 homolog; U5 116KD; U5 small nuclear ribonucleoprotein component; U5 snRNP specific protein, 116 kD; U5 snRNP specific protein, 116 kDa; U5 snRNP-specific protein; U5-116 kDa; U5-116KD; U5S1_HUMAN;
免疫原
- Q15029 U5S1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDTDLYDEFGNYIGPELDSDEDDDELGRETKDLDEMDDDDDDDDVGDHDDDHPGMEVVLHEDKKYYPTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQTLPVTVYEMDFLADLMDNSELIRNVTLCGHLHHGKTCFVDCLIEQTHPEIRKRYDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTPGHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLAVTVCINKIDRLILELKLPPTDAYYKLRHIVDEVNGLISMYSTDENLILSPLLGNVCFSSSQYSICFTLGSFAKIYADTFGDINYQEFAKRLWGDIYFNPKTRKFTKKAPTSSSQRSFVEFILEPLYKILAQVVGDVDTSLPRTLDELGIHLTKEELKLNIRPLLRLVCKKFFGEFTGFVDMCVQHIPSPKVGAKPKIEHTYTGGVDSDLGEAMSDCDPDGPLMCHTTKMYSTDDGVQFHAFGRVLSGTIHAGQPVKVLGENYTLEDEEDSQICTVGRLWISVARYHIEVNRVPAGNWVLIEGVDQPIVKTATITEPRGNEEAQIFRPLKFNTTSVIKIAVEPVNPSELPKMLDGLRKVNKSYPSLTTKVEESGEHVILGTGELYLDCVMHDLRKMYSEIDIKVADPVVTFCETVVETSSLKCFAETPNKKNKITMIAEPLEKGLAEDIENEVVQITWNRKKLGEFFQTKYDWDLLAARSIWAFGPDATGPNILVDDTLPSEVDKALLGSVKDSIVQGFQWGTREGPLCDELIRNVKFKILDAVVAQEPLHRGGGQIIPTARRVVYSAFLMATPRLMEPYYFVEVQAPADCVSAVYTVLARRRGHVTQDAPIPGSPLYTIKAFIPAIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSIVIRPLEPQPAPHLAREFMIKTRRRKGLSEDVSISKFFDDPMLLELAKQDVVLNYPM
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q15029 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| M1 | Acetylation | Uniprot | |
| T3 | Phosphorylation | Uniprot | |
| Y6 | Phosphorylation | Uniprot | |
| S19 | Phosphorylation | Uniprot | |
| T30 | Phosphorylation | Uniprot | |
| K64 | Sumoylation | Uniprot | |
| K64 | Ubiquitination | Uniprot | |
| Y73 | Phosphorylation | Uniprot | |
| T79 | Phosphorylation | Uniprot | |
| T86 | Phosphorylation | Uniprot | |
| T90 | Phosphorylation | Uniprot | |
| K95 | Ubiquitination | Uniprot | |
| K159 | Ubiquitination | Uniprot | |
| Y167 | Phosphorylation | Uniprot | |
| T168 | Phosphorylation | Uniprot | |
| K182 | Ubiquitination | Uniprot | |
| T184 | Phosphorylation | Uniprot | |
| K244 | Ubiquitination | Uniprot | |
| Y336 | Phosphorylation | Uniprot | |
| K341 | Ubiquitination | Uniprot | |
| Y348 | Phosphorylation | Uniprot | |
| K352 | Ubiquitination | Uniprot | |
| T353 | Phosphorylation | Uniprot | |
| K405 | Ubiquitination | Uniprot | |
| K409 | Ubiquitination | Uniprot | |
| S459 | Phosphorylation | Uniprot | |
| S466 | Phosphorylation | Uniprot | |
| S498 | Phosphorylation | Uniprot | |
| K508 | Ubiquitination | Uniprot | |
| S533 | Phosphorylation | Uniprot | |
| K561 | Ubiquitination | Uniprot | |
| T562 | Phosphorylation | Uniprot | |
| T564 | Phosphorylation | Uniprot | |
| T566 | Phosphorylation | Uniprot | |
| R569 | Methylation | Uniprot | |
| K581 | Acetylation | Uniprot | |
| K581 | Ubiquitination | Uniprot | |
| S598 | Phosphorylation | Uniprot | |
| K602 | Ubiquitination | Uniprot | |
| K612 | Ubiquitination | Uniprot | |
| K646 | Ubiquitination | Uniprot | |
| S649 | Phosphorylation | Uniprot | |
| K673 | Ubiquitination | Uniprot | |
| K681 | Ubiquitination | Uniprot | |
| K684 | Ubiquitination | Uniprot | |
| K694 | Ubiquitination | Uniprot | |
| K713 | Ubiquitination | Uniprot | |
| K721 | Ubiquitination | Uniprot | |
| T740 | Phosphorylation | Uniprot | |
| T749 | Phosphorylation | Uniprot | |
| S752 | Phosphorylation | Uniprot | |
| K756 | Ubiquitination | Uniprot | |
| K763 | Ubiquitination | Uniprot | |
| K788 | Ubiquitination | Uniprot | |
| K790 | Acetylation | Uniprot | |
| K790 | Ubiquitination | Uniprot | |
| R803 | Methylation | Uniprot | |
| T811 | Phosphorylation | Uniprot | |
| R813 | Methylation | Uniprot | |
| T824 | Phosphorylation | Uniprot | |
| S866 | Phosphorylation | Uniprot | |
| T885 | Phosphorylation | Uniprot | |
| K936 | Ubiquitination | Uniprot | |
| K941 | Ubiquitination | Uniprot | |
| S944 | Phosphorylation | Uniprot | |
| S948 | Phosphorylation | Uniprot | |
| S950 | Phosphorylation | Uniprot | |
| K951 | Ubiquitination | Uniprot | |
| K963 | Ubiquitination | Uniprot |
研究背景
Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome.
Nucleus.
Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. The U4/U6-U5 tri-snRNP complex is composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39. Component of the pre-catalytic, catalytic and post-catalytic spliceosome complexes. Interacts with ERBB4 and PRPF8. Interacts with PIH1D1. Interacts with RPAP3 and URI1 in a ZNHIT2-dependent manner.
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
研究領域
· Genetic Information Processing > Transcription > Spliceosome.
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