AGPAT4 Antibody - #DF3640
| 製品: | AGPAT4 Antibody |
| カタログ: | DF3640 |
| タンパク質の説明: | Rabbit polyclonal antibody to AGPAT4 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 44 KD; 44kD(Calculated). |
| ユニプロット: | Q9NRZ5 |
| RRID: | AB_2836012 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3640, RRID:AB_2836012.
折りたたみ／展開
1 acyl sn glycerol 3 phosphate acyltransferase delta; 1 acylglycerol 3 phosphate O acyltransferase 4; 1 AGP acyltransferase 4; 1 AGPAT4; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; 1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta); 1-acylglycerol-3-phosphate O-acyltransferase 4; 1-AGP acyltransferase 4; 1-AGPAT 4; AGPAT4; dJ473J16.2; LPAAT delta; LPAAT-delta; Lysophosphatidic acid acyltransferase delta; Lysophosphatidic acid acyltransferase-delta (LPAAT-delta); PLCD_HUMAN; RP3 473J16.2;
免疫原
Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus.
- Q9NRZ5 PLCD_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQLVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKVLAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRFTEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTLLGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMVPPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTEIDKGSAYGNSDSKQKLND
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NRZ5 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K87 | Ubiquitination | Uniprot | |
| S188 | Phosphorylation | Uniprot | |
| K201 | Ubiquitination | Uniprot | |
| S223 | Phosphorylation | Uniprot | |
| Y226 | Phosphorylation | Uniprot | |
| K281 | Ubiquitination | Uniprot | |
| S332 | Phosphorylation | Uniprot | |
| S334 | Phosphorylation | Uniprot | |
| S335 | Phosphorylation | Uniprot | |
| S365 | Phosphorylation | Uniprot | |
| Y367 | Phosphorylation | Uniprot |
研究背景
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (By similarity). Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA) (By similarity).
Endoplasmic reticulum membrane>Multi-pass membrane protein.
Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus.
The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
研究領域
· Environmental Information Processing > Signal transduction > Phospholipase D signaling pathway. (View pathway)
· Metabolism > Lipid metabolism > Glycerolipid metabolism.
· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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