製品: RPL17 Antibody
カタログ: DF3699
タンパク質の説明: Rabbit polyclonal antibody to RPL17
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus
分子量: 24 KD; 21kD(Calculated).
ユニプロット: P18621
RRID: AB_2836063

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 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Zebrafish(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(88%), Dog(100%), Xenopus(100%)
クローナリティ:
Polyclonal
特異性:
RPL17 Antibody detects endogenous levels of total RPL17.
RRID:
AB_2836063
引用形式: Affinity Biosciences Cat# DF3699, RRID:AB_2836063.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

60S ribosomal protein L17; 60S ribosomal protein L23; FLJ92089; Gene encoding putative NFkB activating protein; L17; MGC117162; PD 1; PD-1; PD1; Ribosomal protein L17; RL17_HUMAN; RPL17; rpL23;

免疫原

免疫原:

A synthesized peptide derived from human RPL17, corresponding to a region within C-terminal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
P18621 RL17_HUMAN:

Expressed in pancreas, lung, colon, cystic duct, gall bladder, kidney and liver. Expressed at high levels in the well differentiated pancreatic tumor cell lines HPAF, COLO 357 and Capan-1, the moderately differentiated pancreatic tumor cell lines T3M-4, AsPc-1 and BxPc-3, the poorly differentiated pancreatic tumor cell line MIA PaCa-2, and the pancreatic tumor cell lines of undefined differentiation status such as SW979. Expressed at lower levels in the poorly differentiated pancreatic tumor cell lines HCG-25 and PANC-1.

タンパク質配列:
MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLQKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Rabbit
88
Pig
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P18621 基板として

Site PTM Type Enzyme
S5 Phosphorylation
K13 Ubiquitination
S14 Phosphorylation
C15 S-Nitrosylation
K27 Ubiquitination
K37 Acetylation
K37 Methylation
K37 Sumoylation
K37 Ubiquitination
K49 Acetylation
K49 Ubiquitination
K55 Acetylation
K55 Ubiquitination
R69 Methylation
K74 Acetylation
K74 Ubiquitination
K85 Acetylation
K86 Sumoylation
K86 Ubiquitination
S87 Phosphorylation
K96 Ubiquitination
K105 Ubiquitination
K121 Ubiquitination
T129 Phosphorylation
S141 Phosphorylation
S142 Phosphorylation
K159 Sumoylation
K159 Ubiquitination
K167 Ubiquitination
S171 Phosphorylation

研究背景

機能:

Component of the large ribosomal subunit.

組織特異性:

Expressed in pancreas, lung, colon, cystic duct, gall bladder, kidney and liver. Expressed at high levels in the well differentiated pancreatic tumor cell lines HPAF, COLO 357 and Capan-1, the moderately differentiated pancreatic tumor cell lines T3M-4, AsPc-1 and BxPc-3, the poorly differentiated pancreatic tumor cell line MIA PaCa-2, and the pancreatic tumor cell lines of undefined differentiation status such as SW979. Expressed at lower levels in the poorly differentiated pancreatic tumor cell lines HCG-25 and PANC-1.

サブユニット構造:

Component of the large ribosomal subunit.

タンパク質ファミリー:

Belongs to the universal ribosomal protein uL22 family.

研究領域

· Genetic Information Processing > Translation > Ribosome.

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