ANP32B Antibody - #DF3730
| 製品: | ANP32B Antibody |
| カタログ: | DF3730 |
| タンパク質の説明: | Rabbit polyclonal antibody to ANP32B |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat, Monkey |
| 予測: | Zebrafish, Bovine, Horse, Sheep, Dog |
| 分子量: | 29 KD; 29kD(Calculated). |
| ユニプロット: | Q92688 |
| RRID: | AB_2836094 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3730, RRID:AB_2836094.
折りたたみ／展開
Acidic (leucine rich) nuclear phosphoprotein 32 family member B; Acidic leucine rich nuclear phosphoprotein 32 family member B; Acidic leucine-rich nuclear phosphoprotein 32 family member B; Acidic nuclear phosphoprotein 32 family member B; Acidic protein rich in leucines; AN32B_HUMAN; ANP 32B; ANP32B; APRIL; OTTHUMP0000006377; PAL 31; PAL31; PHAPI 2; PHAPI2; PHAPI2 protein; PHAPI2a; Proliferation related acidic leucine rich protein; Putative HLA-DR-associated protein I-2; Silver stainable protein SSP 29; Silver stainable protein SSP29; Silver-stainable protein SSP29; Ssp 29; Ssp29;
免疫原
- Q92688 AN32B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDMKRRIHLELRNRTPAAVRELVLDNCKSNDGKIEGLTAEFVNLEFLSLINVGLISVSNLPKLPKLKKLELSENRIFGGLDMLAEKLPNLTHLNLSGNKLKDISTLEPLKKLECLKSLDLFNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRETDDEGEDD
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q92688 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R12 | Methylation | Uniprot | |
| T15 | Phosphorylation | Uniprot | |
| C27 | S-Nitrosylation | Uniprot | |
| K33 | Acetylation | Uniprot | |
| K67 | Ubiquitination | Uniprot | |
| K68 | Sumoylation | Uniprot | |
| K68 | Ubiquitination | Uniprot | |
| R75 | Methylation | Uniprot | |
| K86 | Acetylation | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| S96 | Phosphorylation | Uniprot | |
| K99 | Acetylation | Uniprot | |
| K99 | Ubiquitination | Uniprot | |
| K101 | Acetylation | Uniprot | |
| K101 | Ubiquitination | Uniprot | |
| S104 | Phosphorylation | Uniprot | |
| K110 | Acetylation | Uniprot | |
| K116 | Acetylation | Uniprot | |
| K116 | Ubiquitination | Uniprot | |
| S117 | Phosphorylation | Uniprot | |
| T126 | Phosphorylation | Uniprot | |
| K137 | Ubiquitination | Uniprot | |
| Y148 | Phosphorylation | Uniprot | |
| S158 | Phosphorylation | Uniprot | |
| K236 | Acetylation | Uniprot | |
| K239 | Acetylation | Uniprot | |
| T244 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
研究背景
Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity (By similarity). Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome.
Some glutamate residues are glycylated by TTLL8. This modification occurs exclusively on glutamate residues and results in a glycine chain on the gamma-carboxyl group (By similarity).
Nucleus.
Note: Accumulates in the nuclei at the S phase.
Cytoplasm.
Note: Lacks a nuclear localization signal.
Expressed in heart, lung, pancreas, prostate and in spleen, thymus and placenta.
Monomer. Interacts with histones H3 and H4.
Histone binding is mediated by the concave surface of the LRR region.
Belongs to the ANP32 family.
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