製品: SLC25A31 Antibody
カタログ: DF3743
タンパク質の説明: Rabbit polyclonal antibody to SLC25A31
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 35 KD; 35kD(Calculated).
ユニプロット: Q9H0C2
RRID: AB_2836107

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
SLC25A31 Antibody detects endogenous levels of total SLC25A31.
RRID:
AB_2836107
引用形式: Affinity Biosciences Cat# DF3743, RRID:AB_2836107.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

AAC4; Adenine nucleotide translocator 4; ADP; ADP,ATP carrier protein 4; ADP/ATP translocase 4; ADT4_HUMAN; ANT 4; ANT4; ATP carrier protein 4; SFEC; Slc25a31; Solute carrier family 25 member 31; Sperm flagellar energy carrier protein;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9H0C2 ADT4_HUMAN:

Expressed in brain, liver, sperm and testis.

タンパク質配列:
MHREPAKKKAEKRLFDASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASYFGAYDTVKGLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEFFHIDIGGR

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9H0C2 基板として

Site PTM Type Enzyme
S34 Phosphorylation
T36 Phosphorylation
S58 Phosphorylation
Y63 Phosphorylation
Y93 Phosphorylation
T96 Phosphorylation
K104 Acetylation
K104 Ubiquitination
K106 Acetylation
K106 Ubiquitination
S113 Phosphorylation
K117 Ubiquitination
K218 Acetylation
K219 Acetylation
Y261 Phosphorylation
T264 Phosphorylation

研究背景

機能:

Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May serve to mediate energy generating and energy consuming processes in the distal flagellum, possibly as a nucleotide shuttle between flagellar glycolysis, protein phosphorylation and mechanisms of motility.

細胞の位置付け:

Mitochondrion inner membrane>Multi-pass membrane protein. Cell projection>Cilium>Flagellum.
Note: In sperm flagellum this protein is located in the fibrous sheath, a non-mitochondrial region.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in brain, liver, sperm and testis.

タンパク質ファミリー:

The transmembrane helices are not perpendicular to the plane of the membrane, but cross the membrane at an angle. Odd-numbered transmembrane helices exhibit a sharp kink, due to the presence of a conserved proline residue.

Belongs to the mitochondrial carrier (TC 2.A.29) family.

研究領域

· Cellular Processes > Cell growth and death > Necroptosis.   (View pathway)

· Cellular Processes > Cell growth and death > Cellular senescence.   (View pathway)

· Environmental Information Processing > Signal transduction > Calcium signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway.   (View pathway)

· Human Diseases > Neurodegenerative diseases > Parkinson's disease.

· Human Diseases > Neurodegenerative diseases > Huntington's disease.

· Human Diseases > Infectious diseases: Viral > HTLV-I infection.

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