ARFGAP3 Antibody - #DF3748
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3748, RRID:AB_2836112.
折りたたみ／展開
ADP ribosylation factor GTPase activating protein 1; ADP ribosylation factor GTPase activating protein 3; ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3; ARFG3_HUMAN; ArfGAP 3; ARFGAP1; ARFGAP3; FLJ45618;
免疫原
Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.
- Q9NP61 ARFG3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGDPSKQDILTIFKRLRSVPTNKVCFDCGAKNPSWASITYGVFLCIDCSGSHRSLGVHLSFIRSTELDSNWSWFQLRCMQVGGNASASSFFHQHGCSTNDTNAKYNSRAAQLYREKIKSLASQATRKHGTDLWLDSCVVPPLSPPPKEEDFFASHVSPEVSDTAWASAIAEPSSLTSRPVETTLENNEGGQEQGPSVEGLNVPTKATLEVSSIIKKKPNQAKKGLGAKKGSLGAQKLANTCFNEIEKQAQAADKMKEQEDLAKVVSKEESIVSSLRLAYKDLEIQMKKDEKMNISGKKNVDSDRLGMGFGNCRSVISHSVTSDMQTIEQESPIMAKPRKKYNDDSDDSYFTSSSSYFDEPVELRSSSFSSWDDSSDSYWKKETSKDTETVLKTTGYSDRPTARRKPDYEPVENTDEAQKKFGNVKAISSDMYFGRQSQADYETRARLERLSASSSISSADLFEEPRKQPAGNYSLSSVLPNAPDMAQFKQGVRSVAGKLSVFANGVVTSIQDRYGS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NP61 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K14 | Ubiquitination | Uniprot | |
| Y113 | Phosphorylation | Uniprot | |
| K118 | Ubiquitination | Uniprot | |
| S143 | Phosphorylation | Uniprot | |
| S212 | Phosphorylation | Uniprot | |
| K223 | Acetylation | Uniprot | |
| K228 | Acetylation | Uniprot | |
| K229 | Acetylation | Uniprot | |
| S231 | Phosphorylation | Uniprot | |
| K236 | Ubiquitination | Uniprot | |
| K247 | Ubiquitination | Uniprot | |
| K263 | Ubiquitination | Uniprot | |
| S270 | Phosphorylation | Uniprot | |
| S274 | Phosphorylation | Uniprot | |
| Y279 | Phosphorylation | Uniprot | |
| S295 | Phosphorylation | Uniprot | |
| S314 | Phosphorylation | Uniprot | |
| S319 | Phosphorylation | Uniprot | |
| S322 | Phosphorylation | Uniprot | |
| T326 | Phosphorylation | Uniprot | |
| S331 | Phosphorylation | Uniprot | |
| K336 | Ubiquitination | Uniprot | |
| Y341 | Phosphorylation | Uniprot | |
| S348 | Phosphorylation | Uniprot | |
| Y349 | Phosphorylation | Uniprot | |
| T351 | Phosphorylation | Uniprot | |
| S354 | Phosphorylation | Uniprot | |
| S355 | Phosphorylation | Uniprot | |
| Y356 | Phosphorylation | Uniprot | |
| S367 | Phosphorylation | Uniprot | |
| S369 | Phosphorylation | Uniprot | |
| S370 | Phosphorylation | Uniprot | |
| S374 | Phosphorylation | Uniprot | |
| Y378 | Phosphorylation | Uniprot | |
| K380 | Ubiquitination | Uniprot | |
| K392 | Ubiquitination | Uniprot | |
| Y396 | Phosphorylation | Uniprot | |
| T401 | Phosphorylation | Uniprot | |
| K405 | Ubiquitination | Uniprot | |
| Y408 | Phosphorylation | Uniprot | |
| T414 | Phosphorylation | Uniprot | |
| K425 | Ubiquitination | Uniprot | |
| S428 | Phosphorylation | Uniprot | |
| S429 | Phosphorylation | Uniprot | |
| Y432 | Phosphorylation | Uniprot | |
| S437 | Phosphorylation | Uniprot | |
| Y441 | Phosphorylation | Uniprot | |
| T443 | Phosphorylation | Uniprot | |
| S451 | Phosphorylation | Uniprot | |
| S453 | Phosphorylation | Uniprot | |
| S454 | Phosphorylation | Uniprot | |
| S455 | Phosphorylation | Uniprot | |
| S457 | Phosphorylation | Uniprot | |
| S458 | Phosphorylation | Uniprot | |
| K467 | Ubiquitination | Uniprot | |
| Y473 | Phosphorylation | Uniprot | |
| K489 | Ubiquitination | Uniprot | |
| S500 | Phosphorylation | Uniprot | |
| S509 | Phosphorylation | Uniprot | |
| R513 | Methylation | Uniprot |
研究背景
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
Cytoplasm. Golgi apparatus membrane>Peripheral membrane protein>Cytoplasmic side.
Note: Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
Widely expressed. Highest expression in endocrine glands (pancreas, pituitary gland, salivary gland, and prostate) and testis with a much higher expression in the testis than in the ovary.
研究領域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
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