製品: AGXT2L2 Antibody
カタログ: DF3750
タンパク質の説明: Rabbit polyclonal antibody to AGXT2L2
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 50 KD; 50kD(Calculated).
ユニプロット: Q8IUZ5
RRID: AB_2836114

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(91%), Bovine(91%), Horse(91%), Sheep(91%), Rabbit(91%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
AGXT2L2 Antibody detects endogenous levels of total AGXT2L2.
RRID:
AB_2836114
引用形式: Affinity Biosciences Cat# DF3750, RRID:AB_2836114.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

2900006B13Rik; 5-phosphohydroxy-L-lysine phospho-lyase; Alanine glyoxylate aminotransferase 2 like 2; MGC117348; MGC15875; MGC45484; OTTMUSP00000005767; PHLU; PP9286; RP23-79E13.3;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MAADQRPKADTLALRQRLISSSCRLFFPEDPVKIVRAQGQYMYDEQGAEYIDCISNVAHVGHCHPLVVQAAHEQNQVLNTNSRYLHDNIVDYAQRLSETLPEQLCVFYFLNSGSEANDLALRLARHYTGHQDVVVLDHAYHGHLSSLIDISPYKFRNLDGQKEWVHVAPLPDTYRGPYREDHPNPAMAYANEVKRVVSSAQEKGRKIAAFFAESLPSVGGQIIPPAGYFSQVAEHIRKAGGVFVADEIQVGFGRVGKHFWAFQLQGKDFVPDIVTMGKSIGNGHPVACVAATQPVARAFEATGVEYFNTFGGSPVSCAVGLAVLNVLEKEQLQDHATSVGSFLMQLLGQQKIKHPIVGDVRGVGLFIGVDLIKDEATRTPATEEAAYLVSRLKENYVLLSTDGPGRNILKFKPPMCFSLDNARQVVAKLDAILTDMEEKVRSCETLRLQP

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
100
Pig
91
Horse
91
Bovine
91
Sheep
91
Rabbit
91
Zebrafish
55
Xenopus
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8IUZ5 基板として

Site PTM Type Enzyme
K8 Ubiquitination
S20 Phosphorylation
K33 Acetylation
K33 Ubiquitination
Y153 Phosphorylation
K162 Ubiquitination
K278 Ubiquitination
K353 Ubiquitination
K393 Ubiquitination
K439 Ubiquitination

研究背景

機能:

Catalyzes the pyridoxal-phosphate-dependent breakdown of 5-phosphohydroxy-L-lysine, converting it to ammonia, inorganic phosphate and 2-aminoadipate semialdehyde.

細胞の位置付け:

Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Homotetramer.

タンパク質ファミリー:

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

研究領域

· Metabolism > Amino acid metabolism > Lysine degradation.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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