ALDH1B1 Antibody - #DF3755
(1)
(6)
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3755, RRID:AB_2836119.
折りたたみ／展開
Acetaldehyde dehydrogenase 5; AL1B1_HUMAN; Aldehyde dehydrogenase 1 family, member B1; Aldehyde dehydrogenase 1B1; Aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1; Aldehyde dehydrogenase X; Aldehyde dehydrogenase X mitochondrial; ALDH class 2; Aldh1b1; ALDH5; ALDHX; MGC2230; Mitochondrial aldehyde dehydrogenase X; mitochondrial; OTTHUMP00000021399;
免疫原
- P30837 AL1B1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLRFLAPRLLSLQGRTARYSSAAALPSPILNPDIPYNQLFINNEWQDAVSKKTFPTVNPTTGEVIGHVAEGDRADVDRAVKAAREAFRLGSPWRRMDASERGRLLNLLADLVERDRVYLASLETLDNGKPFQESYALDLDEVIKVYRYFAGWADKWHGKTIPMDGQHFCFTRHEPVGVCGQIIPWNFPLVMQGWKLAPALATGNTVVMKVAEQTPLSALYLASLIKEAGFPPGVVNIITGYGPTAGAAIAQHVDVDKVAFTGSTEVGHLIQKAAGDSNLKRVTLELGGKSPSIVLADADMEHAVEQCHEALFFNMGQCCCAGSRTFVEESIYNEFLERTVEKAKQRKVGNPFELDTQQGPQVDKEQFERVLGYIQLGQKEGAKLLCGGERFGERGFFIKPTVFGGVQDDMRIAKEEIFGPVQPLFKFKKIEEVVERANNTRYGLAAAVFTRDLDKAMYFTQALQAGTVWVNTYNIVTCHTPFGGFKESGNGRELGEDGLKAYTEVKTVTIKVPQKNS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P30837 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S11 | Phosphorylation | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| S27 | Phosphorylation | Uniprot | |
| K52 | Ubiquitination | Uniprot | |
| R73 | Methylation | Uniprot | |
| Y135 | Phosphorylation | Uniprot | |
| S217 | Phosphorylation | Uniprot | |
| T283 | Phosphorylation | Uniprot | |
| S330 | Phosphorylation | Uniprot | |
| Y332 | Phosphorylation | Uniprot | |
| K347 | Ubiquitination | Uniprot | |
| K364 | Acetylation | Uniprot | |
| K364 | Ubiquitination | Uniprot | |
| Y373 | Phosphorylation | Uniprot | |
| K379 | Acetylation | Uniprot | |
| K383 | Ubiquitination | Uniprot | |
| K399 | Acetylation | Uniprot | |
| T401 | Phosphorylation | Uniprot | |
| K426 | Ubiquitination | Uniprot | |
| K500 | Ubiquitination | Uniprot |
研究背景
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.
Mitochondrion matrix.
Liver, testis and to a lesser extent in brain.
Homotetramer.
Belongs to the aldehyde dehydrogenase family.
研究領域
· Metabolism > Carbohydrate metabolism > Glycolysis / Gluconeogenesis.
· Metabolism > Carbohydrate metabolism > Ascorbate and aldarate metabolism.
· Metabolism > Lipid metabolism > Fatty acid degradation.
· Metabolism > Amino acid metabolism > Valine, leucine and isoleucine degradation.
· Metabolism > Amino acid metabolism > Lysine degradation.
· Metabolism > Amino acid metabolism > Arginine and proline metabolism.
· Metabolism > Amino acid metabolism > Histidine metabolism.
· Metabolism > Amino acid metabolism > Tryptophan metabolism.
· Metabolism > Metabolism of other amino acids > beta-Alanine metabolism.
· Metabolism > Lipid metabolism > Glycerolipid metabolism.
· Metabolism > Carbohydrate metabolism > Pyruvate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
参考文献
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