AASS Antibody - #DF3763
| 製品: | AASS Antibody |
| カタログ: | DF3763 |
| タンパク質の説明: | Rabbit polyclonal antibody to AASS |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 102 KD; 102kD(Calculated). |
| ユニプロット: | Q9UDR5 |
| RRID: | AB_2836127 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3763, RRID:AB_2836127.
折りたたみ／展開
Alpha aminoadipic semialdehyde synthase mitochondrial; LKR; LKR/SDH; LKRSDH; LOR; LORSDH; Lysine ketoglutarate reductase; Saccharopine dehydrogenase; SDH;
免疫原
- Q9UDR5 AASS_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQPSNRRAIHDKDYVKAGGILQEDISEACLILGVKRPPEEKLMSRKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFMHIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPCEYVEPHELKEVSQTGDLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAGVEGCPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMETIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTLLRGTLRYKGYMKALNGFVKLGLINREALPAFRPEANPLTWKQLLCDLVGISPSSEHDVLKEAVLKKLGGDNTQLEAAEWLGLLGDEQVPQAESILDALSKHLVMKLSYGPEEKDMIVMRDSFGIRHPSGHLEHKTIDLVAYGDINGFSAMAKTVGLPTAMAAKMLLDGEIGAKGLMGPFSKEIYGPILERIKAEGIIYTTQSTIKP
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UDR5 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T51 | Phosphorylation | Uniprot | |
| Y55 | Phosphorylation | Uniprot | |
| K212 | Acetylation | Uniprot | |
| K229 | Acetylation | Uniprot | |
| T263 | Phosphorylation | Uniprot | |
| Y461 | Phosphorylation | Uniprot | |
| S474 | Phosphorylation | Uniprot | |
| T479 | Phosphorylation | Uniprot | |
| S492 | Phosphorylation | Uniprot | |
| K539 | Ubiquitination | Uniprot | |
| Y556 | Phosphorylation | Uniprot | |
| Y700 | Phosphorylation | Uniprot | |
| K707 | Acetylation | Uniprot | |
| Y730 | Phosphorylation | Uniprot | |
| T878 | Phosphorylation | Uniprot | |
| K893 | Ubiquitination | Uniprot |
研究背景
Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively.
Mitochondrion.
Expressed in all 16 tissues examined with highest expression in the liver.
Homodimer.
In the N-terminal section; belongs to the AlaDH/PNT family.
In the C-terminal section; belongs to the saccharopine dehydrogenase family.
研究領域
· Metabolism > Amino acid metabolism > Lysine degradation.
· Metabolism > Global and overview maps > Metabolic pathways.
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