SCNN1D Antibody - #DF3765
| 製品: | SCNN1D Antibody |
| カタログ: | DF3765 |
| タンパク質の説明: | Rabbit polyclonal antibody to SCNN1D |
| アプリケーション: | WB IHC |
| 反応性: | Human |
| 分子量: | 70 KD; 88kD(Calculated). |
| ユニプロット: | P51172 |
| RRID: | AB_2836129 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3765, RRID:AB_2836129.
折りたたみ／展開
Amiloride sensitive sodium channel subunit delta; Amiloride-sensitive sodium channel subunit delta; Delta ENaC; Delta NaCH; Delta-ENaC; Delta-NaCH; DNACH; ENaC Delta; ENaCD; ENaCdelta; Epithelial Na(+) channel subunit delta; MGC149710; MGC149711; Nonvoltage gated sodium channel 1 subunit delta; Nonvoltage-gated sodium channel 1 subunit delta; SCNED; SCNN1D; SCNND_HUMAN; Sodium channel, nonvoltage gated 1, delta;
免疫原
- P51172 SCNND_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRAVLSQKTTPLPRYLWPGHLSGPRRLTWSWCSDHRTPTCRELGSPHPTPCTGPARGWPRRGGGPCGFTSAGHVLCGYPLCLLSGPIQGCGTGLGDSSMAFLSRTSPVAAASFQSRQEARGSILLQSCQLPPQWLSTEAWTGEWKQPHGGALTSRSPGPVAPQRPCHLKGWQHRPTQHNAACKQGQAAAQTPPRPGPPSAPPPPPKEGHQEGLVELPASFRELLTFFCTNATIHGAIRLVCSRGNRLKTTSWGLLSLGALVALCWQLGLLFERHWHRPVLMAVSVHSERKLLPLVTLCDGNPRRPSPVLRHLELLDEFARENIDSLYNVNLSKGRAALSATVPRHEPPFHLDREIRLQRLSHSGSRVRVGFRLCNSTGGDCFYRGYTSGVAAVQDWYHFHYVDILALLPAAWEDSHGSQDGHFVLSCSYDGLDCQARQFRTFHHPTYGSCYTVDGVWTAQRPGITHGVGLVLRVEQQPHLPLLSTLAGIRVMVHGRNHTPFLGHHSFSVRPGTEATISIREDEVHRLGSPYGHCTAGGEGVEVELLHNTSYTRQACLVSCFQQLMVETCSCGYYLHPLPAGAEYCSSARHPAWGHCFYRLYQDLETHRLPCTSRCPRPCRESAFKLSTGTSRWPSAKSAGWTLATLGEQGLPHQSHRQRSSLAKINIVYQELNYRSVEEAPVYSVPQLLSAMGSLCSLWFGASVLSLLELLELLLDASALTLVLGGRRLRRAWFSWPRASPASGASSIKPEASQMPPPAGGTSDDPEPSGPHLPRVMLPGVLAGVSAEESWAGPQPLETLDT
PTMs - P51172 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T229 | Phosphorylation | Uniprot | |
| T232 | Phosphorylation | Uniprot | |
| S242 | Phosphorylation | Uniprot | |
| T296 | Phosphorylation | Uniprot | |
| S339 | Phosphorylation | Uniprot | |
| T341 | Phosphorylation | Uniprot | |
| S363 | Phosphorylation | Uniprot | |
| S506 | Phosphorylation | Uniprot | |
| S508 | Phosphorylation | Uniprot | |
| T513 | Phosphorylation | Uniprot | |
| S735 | Phosphorylation | Uniprot | |
| S790 | Phosphorylation | Uniprot |
研究背景
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Cell membrane>Multi-pass membrane protein.
Heterotrimer containing a delta/SCNN1D, a beta/SCNN1B and a gamma/SCNN1G subunit. The additional delta/SCNN1D subunit exists only in some organisms and can replace the alpha/SCNN1A subunit to form an alternative channel with specific properties.
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1D subfamily.
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