AMPD2 Antibody - #DF3766
| 製品: | AMPD2 Antibody |
| カタログ: | DF3766 |
| タンパク質の説明: | Rabbit polyclonal antibody to AMPD2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 100 KD; 101kD(Calculated). |
| ユニプロット: | Q01433 |
| RRID: | AB_2836130 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3766, RRID:AB_2836130.
折りたたみ／展開
Adenosine monophosphate deaminase 2 (isoform L); Adenosine monophosphate deaminase 2; adenosine monophosphate deaminase 2 isoform L; AMP deaminase 2; AMP deaminase isoform L; AMPD 2; AMPD; AMPD2; AMPD2_HUMAN; RP5-1160K1.5; SPG63;
免疫原
- Q01433 AMPD2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRNRGQGLFRLRSRCFLHQSLPLGAGRRKGLDVAEPGPSRCRSDSPAVAAVVPAMASYPSGSGKPKAKYPFKKRASLQASTAAPEARGGLGAPPLQSARSLPGPAPCLKHFPLDLRTSMDGKCKEIAEELFTRSLAESELRSAPYEFPEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDSDLQLYKEQGEGQGDRSLRERDVLEREFQRVTISGEEKCGVPFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQGPDTPVSADAPVHPPALEQHPYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDIRVGYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q01433 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R2 | Methylation | Uniprot | |
| R4 | Methylation | Uniprot | |
| Q6 | Methylation | Uniprot | |
| S13 | Phosphorylation | Uniprot | |
| S43 | Phosphorylation | Uniprot | |
| S45 | Phosphorylation | Uniprot | |
| S60 | Phosphorylation | Uniprot | |
| S76 | Phosphorylation | Uniprot | |
| R87 | Methylation | Uniprot | |
| S97 | Phosphorylation | Uniprot | |
| R99 | Methylation | Uniprot | |
| S100 | Phosphorylation | Uniprot | |
| K109 | Ubiquitination | Uniprot | |
| T117 | Phosphorylation | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| K124 | Ubiquitination | Uniprot | |
| S134 | Phosphorylation | Uniprot | |
| S138 | Phosphorylation | Uniprot | |
| S142 | Phosphorylation | Uniprot | |
| Y145 | Phosphorylation | Uniprot | |
| S151 | Phosphorylation | Uniprot | |
| S168 | Phosphorylation | Uniprot | |
| K182 | Ubiquitination | Uniprot | |
| K187 | Ubiquitination | Uniprot | |
| T188 | Phosphorylation | Uniprot | |
| S190 | Phosphorylation | Uniprot | |
| S192 | Phosphorylation | Uniprot | |
| Y197 | Phosphorylation | Uniprot | |
| K198 | Ubiquitination | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| K229 | Ubiquitination | Uniprot | |
| C230 | S-Nitrosylation | Uniprot | |
| K242 | Ubiquitination | Uniprot | |
| Y254 | Phosphorylation | Uniprot | |
| K276 | Ubiquitination | Uniprot | |
| T289 | Phosphorylation | Uniprot | |
| S292 | Phosphorylation | Uniprot | |
| Y307 | Phosphorylation | Uniprot | |
| T314 | Phosphorylation | Uniprot | |
| K372 | Sumoylation | Uniprot | |
| K414 | Ubiquitination | Uniprot | |
| K489 | Ubiquitination | Uniprot | |
| K493 | Ubiquitination | Uniprot | |
| Y494 | Phosphorylation | Uniprot | |
| S500 | Phosphorylation | Uniprot | |
| K508 | Ubiquitination | Uniprot | |
| T509 | Phosphorylation | Uniprot | |
| K516 | Acetylation | Uniprot | |
| S527 | Phosphorylation | Uniprot | |
| K533 | Ubiquitination | Uniprot | |
| Y721 | Phosphorylation | Uniprot | |
| K812 | Ubiquitination | Uniprot | |
| R839 | Methylation | Uniprot | |
| S875 | Phosphorylation | Uniprot |
研究背景
AMP deaminase plays a critical role in energy metabolism. Catalyzes the deamination of AMP to IMP and plays an important role in the purine nucleotide cycle.
Methylated at Gln-6 by N6AMT1.
Highly expressed in cerebellum.
Homotetramer.
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
研究領域
· Metabolism > Nucleotide metabolism > Purine metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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