AMPH Antibody - #DF3767
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3767, RRID:AB_2836131.
折りたたみ／展開
Amp; AMPH 1; AMPH; AMPH_HUMAN; AMPH1; Amphiphysin (Stiff-Man syndrome with breast cancer 128kD autoantigen); Amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen); Amphiphysin; Amphiphysin I; CG8604; Damp; dAmph; Dmel\CG8604; HGNC:471; MGC49429; Stiff man syndrome with breast cancer 128kD autoantigen; Stiff man syndrome with breast cancer 128kDa autoantigen;
免疫原
- P49418 AMPH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MADIKTGIFAKNVQKRLNRAQEKVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLHEVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEFNVDLQEELPSLWSRRVGFYVNTFKNVSSLEAKFHKEIAVLCHKLYEVMTKLGDQHADKAFTIQGAPSDSGPLRIAKTPSPPEEPSPLPSPTASPNHTLAPASPAPARPRSPSQTRKGPPVPPLPKVTPTKELQQENIISFFEDNFVPEISVTTPSQNEVPEVKKEETLLDLDFDPFKPEVTPAGSAGVTHSPMSQTLPWDLWTTSTDLVQPASGGSFNGFTQPQDTSLFTMQTDQSMICNLAESEQAPPTEPKAEEPLAAVTPAVGLDLGMDTRAEEPVEEAVIIPGADADAAVGTLVSAAEGAPGEEAEAEKATVPAGEGVSLEEAKIGTETTEGAESAQPEAEELEATVPQEKVIPSVVIEPASNHEEEGENEITIGAEPKETTEDAAPPGPTSETPELATEQKPIQDPQPTPSAPAMGAADQLASAREASQELPPGFLYKVETLHDFEAANSDELTLQRGDVVLVVPSDSEADQDAGWLVGVKESDWLQYRDLATYKGLFPENFTRRLD
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P49418 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K5 | Acetylation | Uniprot | |
| K5 | Ubiquitination | Uniprot | |
| T6 | Phosphorylation | Uniprot | |
| K11 | Acetylation | Uniprot | |
| K15 | Acetylation | Uniprot | |
| K23 | Acetylation | Uniprot | |
| T34 | Phosphorylation | Uniprot | |
| S74 | Phosphorylation | Uniprot | |
| K141 | Ubiquitination | Uniprot | |
| Y145 | Phosphorylation | Uniprot | |
| S147 | Phosphorylation | Uniprot | |
| S210 | Phosphorylation | Uniprot | |
| S211 | Phosphorylation | Uniprot | |
| S250 | Phosphorylation | Uniprot | |
| T260 | Phosphorylation | Uniprot | |
| S262 | Phosphorylation | Q13627 (DYRK1A) | Uniprot |
| S268 | Phosphorylation | Uniprot | |
| S272 | Phosphorylation | Q00535 (CDK5) , P06493 (CDK1) , Q13627 (DYRK1A) | Uniprot |
| S276 | Phosphorylation | Q00535 (CDK5) , P06493 (CDK1) , Q13627 (DYRK1A) | Uniprot |
| S285 | Phosphorylation | P06493 (CDK1) , Q00535 (CDK5) , Q13627 (DYRK1A) | Uniprot |
| S293 | Phosphorylation | Q13627 (DYRK1A) , O76039 (CDKL5) , P28482 (MAPK1) , P27361 (MAPK3) | Uniprot |
| S295 | Phosphorylation | P28482 (MAPK1) , Q13627 (DYRK1A) , P27361 (MAPK3) | Uniprot |
| T310 | Phosphorylation | Q13627 (DYRK1A) | Uniprot |
| T312 | Phosphorylation | Q13627 (DYRK1A) | Uniprot |
| T350 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| T387 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
| T445 | Phosphorylation | Uniprot | |
| T456 | Phosphorylation | Uniprot | |
| S506 | Phosphorylation | Uniprot | |
| S549 | Phosphorylation | Uniprot | |
| K683 | Ubiquitination | Uniprot |
研究背景
May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
Cytoplasmic vesicle>Secretory vesicle>Synaptic vesicle membrane>Peripheral membrane protein>Cytoplasmic side. Cytoplasm>Cytoskeleton.
Neurons, certain endocrine cell types and spermatocytes.
Heterodimer with BIN1 (By similarity). Binds SH3GLB1 (By similarity). Interacts with REPS1 and SGIP1. Binds AP2A2. Interacts with AP2B1. Interacts with DNM1 AND SYNJ1 (By similarity).
研究領域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
· Organismal Systems > Immune system > Fc gamma R-mediated phagocytosis. (View pathway)
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