APOL1 Antibody - #DF3785
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3785, RRID:AB_2836142.
折りたたみ／展開
APO L; Apo-L; ApoL; APOL I; ApoL-I; APOL1; APOL1_HUMAN; APOLI; Apolipoprotein L; Apolipoprotein L I; Apolipoprotein L-I; Apolipoprotein L1; FSGS4;
免疫原
Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen.
- O14791 APOL1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEGAALLRVSVLCIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIEDAIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKNWHDKGQQYRNWFLKEFPRLKSELEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISSGILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTMDYGKKWWTQAQAHDLVIKSLDKLKEVREFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASASRPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLHEGAKSETAEELKKVAQELEEKLNILNNNYKILQADQEL
PTMs - O14791 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K148 | Ubiquitination | Uniprot | |
| T236 | O-Glycosylation | Uniprot | |
| N261 | N-Glycosylation | Uniprot | |
| T307 | Phosphorylation | Uniprot | |
| S311 | Phosphorylation | Uniprot | |
| S314 | Phosphorylation | Uniprot |
研究背景
May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.
Phosphorylated by FAM20C in the extracellular medium.
Secreted.
Plasma. Found on APOA-I-containing high density lipoprotein (HDL3). Expressed in pancreas, lung, prostate, liver, placenta and spleen.
In plasma, interacts with APOA1 and mainly associated with large high density lipoprotein particles.
Belongs to the apolipoprotein L family.
研究領域
· Human Diseases > Infectious diseases: Parasitic > African trypanosomiasis.
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