ABCB10 Antibody - #DF3811
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3811, RRID:AB_2836168.
折りたたみ／展開
ABC transporter 10 protein; ABCB10; ABCB10 ATP binding cassette, sub family B (MDR/TAP), member 10; ABCBA_HUMAN; ATP binding cassette sub family B member 10, mitochondrial; ATP binding cassette transporter 10; ATP-binding cassette sub-family B member 10; ATP-binding cassette transporter 10; EST20237; M ABC2; M-ABC2; mitochondrial; Mitochondrial ATP binding cassette 2; Mitochondrial ATP-binding cassette 2; MTABC2;
免疫原
Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon.
- Q9NRK6 ABCBA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRGPPAWPLRLLEPPSPAEPGRLLPVACVWAAASRVPGSLSPFTGLRPARLWGAGPALLWGVGAARRWRSGCRGGGPGASRGVLGLARLLGLWARGPGSCRCGAFAGPGAPRLPRARFPGGPAAAAWAGDEAWRRGPAAPPGDKGRLRPAAAGLPEARKLLGLAYPERRRLAAAVGFLTMSSVISMSAPFFLGKIIDVIYTNPTVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQTSGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLSDGLRAGAQASVGISMMFFVSPNLATFVLSVVPPVSIIAVIYGRYLRKLTKVTQDSLAQATQLAEERIGNVRTVRAFGKEMTEIEKYASKVDHVMQLARKEAFARAGFFGATGLSGNLIVLSVLYKGGLLMGSAHMTVGELSSFLMYAFWVGISIGGLSSFYSELMKGLGAGGRLWELLEREPKLPFNEGVILNEKSFQGALEFKNVHFAYPARPEVPIFQDFSLSIPSGSVTALVGPSGSGKSTVLSLLLRLYDPASGTISLDGHDIRQLNPVWLRSKIGTVSQEPILFSCSIAENIAYGADDPSSVTAEEIQRVAEVANAVAFIRNFPQGFNTVVGEKGVLLSGGQKQRIAIARALLKNPKILLLDEATSALDAENEYLVQEALDRLMDGRTVLVIAHRLSTIKNANMVAVLDQGKITEYGKHEELLSKPNGIYRKLMNKQSFISA
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NRK6 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S80 | Phosphorylation | Uniprot | |
| K159 | Ubiquitination | Uniprot | |
| Y207 | Phosphorylation | Uniprot | |
| S208 | Phosphorylation | Uniprot | |
| T212 | Phosphorylation | Uniprot | |
| K265 | Acetylation | Uniprot | |
| K265 | Ubiquitination | Uniprot | |
| T363 | Phosphorylation | Uniprot | |
| K369 | Ubiquitination | Uniprot | |
| K380 | Ubiquitination | Uniprot | |
| K486 | Ubiquitination | Uniprot | |
| K732 | Ubiquitination | Uniprot |
研究背景
May mediate critical mitochondrial transport functions related to heme biosynthesis.
Mitochondrion inner membrane>Multi-pass membrane protein.
Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon.
Homodimer or homooligomer. Interacts with C10orf88/PAAT.
Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.
研究領域
· Environmental Information Processing > Membrane transport > ABC transporters.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.