ABCB7 Antibody - #DF3812
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3812, RRID:AB_2836169.
折りたたみ／展開
ABC transporter 7 protein; ABC7; Abcb7; ABCB7_HUMAN; ASAT; Atm1p; ATP binding cassette 7; ATP binding cassette sub family B (MDR/TAP) member 7; ATP binding cassette sub family B member 7; ATP binding cassette sub family B member 7 mitochondrial; ATP binding cassette transporter 7; ATP-binding cassette sub-family B member 7; ATP-binding cassette transporter 7; EST140535; MDR7; mitochondrial; Multidrug resistance protein 7; P-glycoprotein 7; PGP7;
免疫原
- O75027 ABCB7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MALLAMHSWRWAAAAAAFEKRRHSAILIRPLVSVSGSGPQWRPHQLGALGTARAYQIPESLKSITWQRLGKGNSGQFLDAAKALQVWPLIEKRTCWHGHAGGGLHTDPKEGLKDVDTRKIIKAMLSYVWPKDRPDLRARVAISLGFLGGAKAMNIVVPFMFKYAVDSLNQMSGNMLNLSDAPNTVATMATAVLIGYGVSRAGAAFFNEVRNAVFGKVAQNSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALVFNLLPIMFEVMLVSGVLYYKCGAQFALVTLGTLGTYTAFTVAVTRWRTRFRIEMNKADNDAGNAAIDSLLNYETVKYFNNERYEAQRYDGFLKTYETASLKSTSTLAMLNFGQSAIFSVGLTAIMVLASQGIVAGTLTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLKVDTQIKDKVMASPLQITPQTATVAFDNVHFEYIEGQKVLSGISFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQKGSIYLAGQNIQDVSLESLRRAVGVVPQDAVLFHNTIYYNLLYGNISASPEEVYAVAKLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKDPPVILYDEATSSLDSITEETILGAMKDVVKHRTSIFIAHRLSTVVDADEIIVLDQGKVAERGTHHGLLANPHSIYSEMWHTQSSRVQNHDNPKWEAKKENISKEEERKKLQEEIVNSVKGCGNCSC
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75027 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R10 | Methylation | Uniprot | |
| Y196 | Phosphorylation | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| K216 | Acetylation | Uniprot | |
| K216 | Ubiquitination | Uniprot | |
| S243 | Phosphorylation | Uniprot | |
| K251 | Acetylation | Uniprot | |
| K251 | Ubiquitination | Uniprot | |
| T257 | Phosphorylation | Uniprot | |
| S261 | Phosphorylation | Uniprot | |
| S265 | Phosphorylation | Uniprot | |
| Y340 | Phosphorylation | Uniprot | |
| K344 | Ubiquitination | Uniprot | |
| S370 | Phosphorylation | Uniprot | |
| T371 | Phosphorylation | Uniprot | |
| T446 | Phosphorylation | Uniprot | |
| S489 | Phosphorylation | Uniprot | |
| S492 | Phosphorylation | Uniprot | |
| K499 | Acetylation | Uniprot | |
| K500 | Ubiquitination | Uniprot | |
| T600 | Phosphorylation | Uniprot | |
| K608 | Ubiquitination | Uniprot | |
| S660 | Phosphorylation | Uniprot | |
| S743 | Phosphorylation | Uniprot |
研究背景
Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
Mitochondrion inner membrane>Multi-pass membrane protein.
Homodimer or heterodimer. Interacts with C10orf88/PAAT.
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
研究領域
· Environmental Information Processing > Membrane transport > ABC transporters.
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