DHX8 Antibody - #DF3822
| 製品: | DHX8 Antibody |
| カタログ: | DF3822 |
| タンパク質の説明: | Rabbit polyclonal antibody to DHX8 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 150 KD; 139kD(Calculated). |
| ユニプロット: | Q14562 |
| RRID: | AB_2836179 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3822, RRID:AB_2836179.
折りたたみ／展開
ATP dependent RNA helicase DHX8; ATP-dependent RNA helicase dhx8; DDX 8; DDX8; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 (RNA helicase); DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8; DEAD/H box 8; DEAD/H box polypeptide 8; DEAH (Asp Glu Ala His) box polypeptide 8; DEAH box polypeptide 8; DEAH box protein 8; DHX 8; dhx8; DHX8_HUMAN; HRH 1; HRH1; PRP 22; PRP22; PRP22, S. cerevisiae, homolog of; PRPF 22; PRPF22; RNA helicase HRH 1; RNA helicase HRH1;
免疫原
- Q14562 DHX8_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAVAVAMAGALIGSEPGPAEELAKLEYLSLVSKVCTELDNHLGINDKDLAEFVISLAEKNTTFDTFKASLVKNGAEFTDSLISNLLRLIQTMRPPAKPSTSKDPVVKPKTEKEKLKELFPVLCQPDNPSVRTMLDEDDVKVAVDVLKELEALMPSAAGQEKQRDAEHRDRTKKKKRSRSRDRNRDRDRDRERNRDRDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDRWRDKHVDRPPPEEPTIGDIYNGKVTSIMQFGCFVQLEGLRKRWEGLVHISELRREGRVANVADVVSKGQRVKVKVLSFTGTKTSLSMKDVDQETGEDLNPNRRRNLVGETNEETSMRNPDRPTHLSLVSAPEVEDDSLERKRLTRISDPEKWEIKQMIAANVLSKEEFPDFDEETGILPKVDDEEDEDLEIELVEEEPPFLRGHTKQSMDMSPIKIVKNPDGSLSQAAMMQSALAKERRELKQAQREAEMDSIPMGLNKHWVDPLPDAEGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRLEPLYNRYEEPNAWRISRAFRRR
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q14562 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S14 | Phosphorylation | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| S177 | Phosphorylation | Uniprot | |
| S179 | Phosphorylation | Uniprot | |
| S224 | Phosphorylation | Uniprot | |
| S226 | Phosphorylation | Uniprot | |
| S228 | Phosphorylation | Uniprot | |
| S230 | Phosphorylation | Uniprot | |
| Y241 | Phosphorylation | Uniprot | |
| T263 | Phosphorylation | Uniprot | |
| T273 | Phosphorylation | Uniprot | |
| T327 | Phosphorylation | Uniprot | |
| S334 | Phosphorylation | Uniprot | |
| T358 | Phosphorylation | Uniprot | |
| T362 | Phosphorylation | Uniprot | |
| S377 | Phosphorylation | Uniprot | |
| S385 | Phosphorylation | Uniprot | |
| S395 | Phosphorylation | Uniprot | |
| K399 | Sumoylation | Uniprot | |
| K399 | Ubiquitination | Uniprot | |
| S412 | Phosphorylation | Uniprot | |
| S456 | Phosphorylation | Uniprot | |
| S460 | Phosphorylation | Uniprot | |
| K539 | Methylation | Uniprot | |
| K547 | Ubiquitination | Uniprot | |
| T554 | Phosphorylation | Uniprot | |
| S557 | Phosphorylation | Uniprot | |
| K628 | Ubiquitination | Uniprot | |
| T694 | Phosphorylation | Uniprot | |
| K868 | Ubiquitination | Uniprot | |
| K885 | Ubiquitination | Uniprot | |
| T914 | Phosphorylation | Uniprot | |
| T915 | Phosphorylation | Uniprot | |
| S996 | Phosphorylation | Uniprot | |
| K1090 | Ubiquitination | Uniprot | |
| K1098 | Ubiquitination | Uniprot | |
| K1105 | Ubiquitination | Uniprot | |
| T1126 | Phosphorylation | Uniprot | |
| Y1202 | Phosphorylation | Uniprot | |
| Y1205 | Phosphorylation | Uniprot |
研究背景
Involved in pre-mRNA splicing as component of the spliceosome. Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
Nucleus.
Identified in the spliceosome C complex. Interacts with ARRB2; the interaction is detected in the nucleus upon OR1D2 stimulation.
The RS domain confers a nuclear localization signal, and appears to facilitate the interaction with the spliceosome.
Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily.
研究領域
· Genetic Information Processing > Transcription > Spliceosome.
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